4-acetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | 101439-02-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 4-acetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
• 英文别名: 1-Acetoxy-anthrachinon-3-carbonsaeure；4-Acetoxy-9,10-dioxo-9,10-dihydro-anthracen-2-carbonsaeure；4-Acetyloxy-9,10-dioxoanthracene-2-carboxylic acid；4-acetyloxy-9,10-dioxoanthracene-2-carboxylic acid
• CAS: 101439-02-5
• 化学式: C₁₇H₁₀O₆
• 分子量: 310.263
• InChiKey: RIKDKLVLOGEGNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  97.7
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-acetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid 在 Pd-BaSO₄ 、 氯化亚砜 、 xylene 作用下， 生成 9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarbaldehyde
  参考文献：
  名称：

  Mitter; Das-Gupta; Bachhwat, Journal of the Indian Chemical Society, 1934, vol. 11, p. 893,896

  摘要：

  DOI：
• 作为产物：
  描述：

  1-Acetoxy-3-methyl-anthrachinon 在 chromium(VI) oxide 、 乙酸酐 、 溶剂黄146 作用下， 生成 4-acetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
  参考文献：
  名称：

  [EN] NOVEL COMPOUNDS TO TREAT CYTOKINE RELATED DISORDERS
  [FR] NOUVEAUX COMPOSÉS POUR TRAITER DES TROUBLES LIÉS À LA CYTOKINE

  摘要：

  The present invention relates to novel compounds of the general formula (I) having the potential to treat cytokine related disorders, their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.

  公开号：

  WO2023199238A1

文献信息

• METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION
  申请人：ZHUHAI QiWEl BIO-TECHNOLOGY LTD.

  公开号：US20220016146A1

  公开（公告）日：2022-01-20

  Provided herein are compounds/compositions that are useful for killing or inhibiting the growth of a microorganism, such as Bacillus megaterium . Also provided herein are methods of using the compounds/compositions for treating infections with a microorganism, such as Bacillus megaterium and for treating or preventing diseases or disorders associated with such infections, such as AMD.