1,3-Dioxolane-2-carboxylic acid, 4,4,5-trifluoro-2,5-bis(trifluoromethyl)- | 847685-12-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3-Dioxolane-2-carboxylic acid, 4,4,5-trifluoro-2,5-bis(trifluoromethyl)-
• 英文别名: 4,4,5-trifluoro-2,5-bis(trifluoromethyl)-1,3-dioxolane-2-carboxylic acid
• CAS: 847685-12-5
• 化学式: C₆HF₉O₄
• 分子量: 308.05
• InChiKey: SIJLTAVFEHEPTJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  13

文献信息

• METHOD OF PRODUCING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE)
  申请人：TOSOH CORPORATION

  公开号：US20220002262A1

  公开（公告）日：2022-01-06

  Provided is a method of producing perfluoro(2-methylene-4-methyl-1,3-dioxolane), the method including at least following processes (1) to (3): (1) reacting at least one of perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) and a hydrolysis product thereof with a basic aqueous solution containing one or more cations selected from the group consisting of alkali metal ions and alkaline earth metal ions and then separating a liquid containing produced perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts by a liquid separation operation; (2) performing one or more water content reduction treatments selected from the group consisting of water evaporation and water adsorption on the liquid containing the obtained perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts to obtain perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts in a solution state or a solid state; and (3) causing a decarboxylation reaction in a liquid phase system with the obtained perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts in a solution state or a solid state to produce perfluoro(2-methylene-4-methyl-1,3-dioxolane).

  提供了一种制备全氟(2-亚甲基-4-甲基-1,3-二氧杂环己烷)的方法，该方法包括至少以下步骤(1)至(3)：(1)将至少一种全氟(2,4-二甲基-2-氟甲酰基-1,3-二氧杂环己烷)及其水解产物与含有选自碱金属离子和碱土金属离子的阳离子的碱性水溶液反应，然后通过液体分离操作分离出含有产生的全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱土金属盐的液体；(2)对所得到的含有全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱土金属盐的液体进行选自水蒸发和水吸附的一种或多种水分减少处理，以获得溶液状态或固态的全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱土金属盐；以及(3)在溶液状态或固态的全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧杂环己烷-2-基)羧酸碱土金属盐的存在下，在液相体系中进行脱羧反应，以产生全氟(2-亚甲基-4-甲基-1,3-二氧杂环己烷)。
• FLUOROLACTONE AND METHOD FOR PRODUCING SAME
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：US20210371392A1

  公开（公告）日：2021-12-02

  The present disclosure provides, for example, a method that can produce a fluorolactone compound from hexafluoropropylene oxide or the like in a single step. The present disclosure relates to a method for producing a compound represented by formula (1): wherein two R 1 are the same and each is a fluorine atom or a fluoroalkyl group, the method comprising step A of reacting a compound represented by formula (2): wherein R 1 is as defined above, with a compound (3) represented by formula (3-1) or the like: wherein R 31 , R 32 , and R 33 are the same or different and each is a hydrogen atom or a C 1-10 alkyl group, or two of them are optionally linked to each other to form a ring optionally having one or more substituents, in the presence of a fluorine compound (4) represented by formula (4-1) or the like: MH n F m (4-1) wherein M is a metal atom, n is 0 or 1, and the sum of the valence number of M and n is m, and an organic solvent, provided that the compound represented by formula (3) is excluded from the organic solvent.

  本公开提供了一种方法，例如可以通过单步反应从六氟丙烯氧化物或类似物质产生氟代内酯化合物。本公开涉及一种用于生产由式（1）表示的化合物的方法：其中两个R1相同，每个是氟原子或氟代烷基，该方法包括步骤A，其通过将由式（2）表示的化合物与由式（3-1）表示的化合物或类似化合物反应：其中R1如上所定义，R31、R32和R33相同或不同，每个是氢原子或C1-10烷基，或其中两个可以选配地连接在一起形成具有一个或多个取代基的环，在氟化物化合物（4-1）或类似化合物的存在下，在有机溶剂的存在下，前提是由式（3）表示的化合物被排除在有机溶剂之外。
• PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE) PRODUCTION METHOD
  申请人：Tosoh Corporation

  公开号：EP3878845A1

  公开（公告）日：2021-09-15

  Provided is a method of producing perfluoro(2-methylene-4-methyl-1,3-dioxolane), the method including at least following processes (1) to (3): (1) reacting at least one of perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) and a hydrolysis product thereof with a basic aqueous solution containing one or more cations selected from the group consisting of alkali metal ions and alkaline earth metal ions and then separating a liquid containing produced perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts by a liquid separation operation; (2) performing one or more water content reduction treatments selected from the group consisting of water evaporation and water adsorption on the liquid containing the obtained perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts to obtain perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts in a solution state or a solid state; and (3) causing a decarboxylation reaction in a liquid phase system with the obtained perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkali metal salts or perfluoro(2,4-dimethyl-1,3-dioxolane-2-yl)carboxylic acid alkaline earth metal salts in a solution state or a solid state to produce perfluoro(2-methylene-4-methyl-1,3-dioxolane).

  提供了一种生产全氟(2-亚甲基-4-甲基-1,3-二氧戊环)的方法，该方法至少包括以下过程(1)至(3)： (1) 将全氟(2,4-二甲基-2-氟甲酰-1,3-二氧戊环)及其水解产物中的至少一种与含有一种或多种选自碱金属离子和碱土金属离子组成的组中的阳离子的碱性水溶液反应，然后分离出含有生成的全氟(2,4-二甲基-2-氟甲酰-1,3-二氧戊环)的液体、4-二甲基-1,3-二氧戊环-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱土金属盐的液体进行液体分离操作； (2) 对含有所获得的全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1、全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱土金属盐，得到溶液状态或固体状态的全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱金属盐；和 (3) 在液相体系中，使获得的全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱金属盐或全氟(2,4-二甲基-1,3-二氧戊环-2-基)羧酸碱土金属盐在溶液态或固态下发生脱羧反应，生成全氟(2-亚甲基-4-甲基-1,3-二氧戊环)。
• METHOD FOR STABILIZING PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE)-CONTAINING COMPOSITION AND STABILIZED PERFLUORO(2-METHYLENE-4-METHYL-1,3-DIOXOLANE)-CONTAINING COMPOSITION
  申请人：Tosoh Corporation

  公开号：EP3901144A1

  公开（公告）日：2021-10-27

  A method of stabilizing perfluoro(2-methylene-4-methyl-1,3-dioxolane) (hereinafter simply referred to as a "stabilization method"), including incorporating at least one selected from the group consisting of a hydroxy group-containing fluoroaromatic compound represented by General Formula (1) below and a hydroxy group-containing fluoroaromatic compound represented by General Formula (2) below into a composition containing perfluoro(2-methylene-4-methyl-1,3-dioxolane): (in the formula, R1 to R6 each independently represent one selected from the group consisting of a fluorine atom, a perfluoroalkyl group and a hydroxy group, and at least one of R1 to R6 is a hydroxy group); (in the formula, R7 to R14 each independently represent one selected from the group consisting of a fluorine atom, a perfluoroalkyl group and a hydroxy group, and at least one of R7 to R14 is a hydroxy group).

  一种稳定全氟(2-亚甲基-4-甲基-1,3-二氧戊环)的方法(以下简称 "稳定方法")，包括在含有全氟(2-亚甲基-4-甲基-1,3-二氧戊环)的组合物中加入至少一种选自下式(1)所代表的含羟基的氟芳烃化合物和下式(2)所代表的含羟基的氟芳烃化合物的组： (式中，R1 至 R6 各自独立地代表选自由氟原子、全氟烷基和羟基组成的组，且 R1 至 R6 中至少有一个是羟基)； (式中，R7 至 R14 各自独立地代表选自由氟原子、全氟烷基和羟基组成的组中的一 个，且 R7 至 R14 中至少有一个是羟基）。
• METHOD FOR PRODUCING FLUORINATED 1,3-DIOXOLANE COMPOUNDS, FLUORINATED 1,3-DIOXOLANE COMPOUNDS, FLUORINATED POLYMERS OF THE FLUORINATED 1,3-DIOXOLANE COMPOUNDS, AND OPTICAL OR ELECTRICAL MATERIALS USING THE POLYMERS
  申请人：Japan Science and Technology Agency

  公开号：EP1658278B1

  公开（公告）日：2010-03-31