Mitemcinal fumarate | 154802-96-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Mitemcinal fumarate
• 英文别名: (E)-but-2-enedioic acid;(2S,4R,5R,8R,9S,10S,11R,12R)-5-ethyl-9-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-11-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-4-methoxy-2,4,8,10,12,14-hexamethyl-6,15-dioxabicyclo[10.2.1]pentadec-1(14)-ene-3,7-dione
• CAS: 154802-96-7
• 化学式: C84H142N2O28
• 分子量: 1628.0
• InChiKey: KQRXEQGYUDDPNW-QXRSSOOUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.78
• 重原子数：
  114
• 可旋转键数：
  20
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  378
• 氢给体数：
  6
• 氢受体数：
  30

文献信息

• Compositions and methods for treating gastrointestinal hypomotility and associated disorders
  申请人：Ashburn T. Ted

  公开号：US20070010543A1

  公开（公告）日：2007-01-11

  This invention relates to methods for treating, preventing and/or managing GI hypomotility or a disorder associated with GI hypomotility in a subject including administering to the subject two compounds, where the first compound is a 5HT 3 agonist and where the combination of the two compounds results in an increase in GI motility. Also provided are compositions and kits for use in methods of the invention.
• US7927613B2
  申请人：——

  公开号：US7927613B2

  公开（公告）日：2011-04-19