甲基葡萄糖胺乳清酸盐 | 59404-17-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 甲基葡萄糖胺乳清酸盐
• 英文名称: Methylglucaminorotat
• 英文别名: Methylglucamine orotate；2,4-dioxo-1H-pyrimidine-6-carboxylic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
• CAS: 59404-17-0
• 化学式: C₅H₄N₂O₄*C₇H₁₇NO₅
• 分子量: 351.313
• InChiKey: QXWPJYVLNHANJZ-LJTMIZJLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.6
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  209
• 氢给体数：
  9
• 氢受体数：
  10

文献信息

• [EN] COMPOSITION FOR ENHANCING BIOSYNTHESIS OF HYALURONIC ACID OR GLYCOSAMINOGLYCAN COMPRISING OROTIC ACID, A SALT THEREOF, OR A DERIVATIVE THEREOF<br/>[FR] COMPOSITION DESTINÉE À AMPLIFIER LA BIOSYNTHÈSE D'ACIDE HYALURONIQUE OU DE GLYCOSAMINOGLYCANE COMPRENANT DE L'ACIDE OROTIQUE, L'UN DE SES SELS OU L'UN DE SES DÉRIVÉS
  申请人：MAZENCE INC

  公开号：WO2010005123A1

  公开（公告）日：2010-01-14

  The present invention relates to a composition for enhancing biosynthesis of hyaluronic acid or glycosaminoglycan comprising orotic acid, a salt thereof, or a derivative thereof. The composition comprising orotic acid, a salt thereof, or a derivative thereof according to the present invention can be used for preventing, treating or improving arthritis, disk, skin aging, wrinkle, scheroma, ophthalmic diseases, wound, scar, colpoxerosis, gum diseases, interstitial cystitis, atopic dermatitis or xeroderma, etc. which can be caused by decline of production and hypofunction of hyaluronic acid or glycosaminoglycan.