甲氧基-1-甲基-4-环己烯-1 | 52662-20-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 甲氧基-1-甲基-4-环己烯-1
• 英文名称: methoxy-1 methyl-4 cyclohexene-1
• 英文别名: 2,3,4,5-Tetrahydro-4-methylanisol；methyl-(4-methyl-cyclohex-1-enyl)-ether；(+/-)-4-Methoxy-1-methyl-cyclohexen-(3)；Methyl-(4-methyl-cyclohex-1-enyl)-aether；1-methoxy-4-methylcyclohexene
• CAS: 52662-20-1
• 化学式: C₈H₁₄O
• 分子量: 126.199
• InChiKey: UIZJMGJALWBCRF-UHFFFAOYSA-N

物化性质

• 熔点：
  157-162 °C
• 沸点：
  75 °C(Press: 56 Torr)
• 密度：
  0.88±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  甲氧基-1-甲基-4-环己烯-1 生成 4-甲基环己酮
  参考文献：
  名称：

  327.通过溶解金属进行还原。第五部分

  摘要：

  DOI：

  10.1039/jr9470001642
• 作为产物：
  描述：

  2,5-dihydro-4-methylanisole 在 乙醇 、 氨 、 sodium 作用下， 生成 甲氧基-1-甲基-4-环己烯-1
  参考文献：
  名称：

  327.通过溶解金属进行还原。第五部分

  摘要：

  DOI：

  10.1039/jr9470001642

文献信息

• [EN] PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH<br/>[FR] COMPOSÉS DE PYRAZOLE PYRAMINE AMINE EN TANT QU'INHIBITEURS DE KINASE, COMPOSITIONS LES CONTENANT ET PROCÉDÉ DE TRAITEMENT LES EMPLOYANT
  申请人：SIGNAL PHARM LLC

  公开号：WO2009089042A1

  公开（公告）日：2009-07-16

  Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure:Formula (I). Wherein Q and R1-R3 are as defined herein, compositions comprising an effective amount of a Pyrazole Pyrazine Amine Compound and methods for treating or preventing inflammatory conditions, immunological conditions, cancer, neurodegenerative diseases, age-related diseases, cardiovascular diseases and metabolic conditions, or conditions treatable or preventable by inhibition of an IKK, or an IKK pathway, comprising administering an effective amount of a Pyrazole Pyrazine Amine Compound to a patient in need thereof.

  本文提供了具有以下结构的吡唑吡嗪胺化合物：Formula (I)。其中Q和R1-R3如本文所定义，包括有效量的吡唑吡嗪胺化合物的组合物，以及用于治疗或预防炎症症状、免疫症状、癌症、神经退行性疾病、与年龄相关的疾病、心血管疾病和代谢症状，或通过抑制IKK或IKK途径可治疗或预防的疾病，包括向需要的患者施用有效量的吡唑吡嗪胺化合物的方法。
• Reaction of Enol Ethers with the I2-H2O2 System: Synthesis of 2-Iodo-1-methoxy Hydroperoxides and Their Deperoxidation and Demethoxylation to 2-Iodo Ketones
  作者：Alexander Terent’ev、Alexander Borisov、Maxim Platonov、Zoya Starikova、Vladimir Chernyshev、Gennady Nikishin

  DOI：10.1055/s-0029-1217062

  日期：——

  The reaction of enol ethers with the I2-H2O2 system in diethyl ether affords 2-iodo ketones and the previously unknown 2-iodo-1-methoxy hydroperoxides. In the presence of the I2-H2O2 system, the latter compounds undergo deperoxidation and demethoxylation to form 2-iodo ketones. The reaction conditions were found for the synthesis of 2-iodo ketones from enol ethers in 67-94% yields.

  酮烯醚与I2-H2O2体系在乙醚中反应生成2-碘酮和之前未知的2-碘-1-甲氧基过氧化氢。在I2-H2O2体系存在的情况下，后者化合物发生去过氧化和去甲氧基反应，形成2-碘酮。研究发现了从酮烯醚合成2-碘酮的反应条件，产率为67-94%。
• The synthesis of tricyclic naphtho[b] fused frameworks via isoquinolinium salts
  作者：Richard W. Franck、Ram B. Gupta

  DOI：10.1016/s0040-4039(01)80800-5

  日期：——

  The cycloaddition of the enol ethers of cyclic ketones with isoquinolinium salts is the key step in a general preparation of interesting tricyclic naphthalene derivatives.

  环酮的烯醇醚与异喹啉鎓盐的环加成是常规制备有趣的三环萘衍生物的关键步骤。
• Infrared intensities as a measure of intramolecular interactions. Part XXXVI. Field-induced resonance effects
  作者：Trevor J. Broxton、Graeme Butt、Richard Liu、Lay H. Teo、Ronald D. Topsom、Alan R. Katritzky

  DOI：10.1039/p29740000463

  日期：——

  The variation of the νCC intensity for a series of disubstituted cyclohexenes indicates that the resonance interaction of a substituent with the unsaturated system can be altered by a second remote substituent. This effect is ascribed to the operation of a field-induced resonace effect.

  在ν的变化Ç Ç强度的一系列二取代的环己烯的指示与所述不饱和体系的取代基的共振相互作用可通过第二远程取代基被改变。该效应归因于场致共振效应的作用。
• APPLICATION OF ?-QUATERNARY AMMONIUM BUTYRATE COMPOUND IN PREPARATION OF ANIMAL FEED ADDITIVE
  申请人：Peng, Xianfeng

  公开号：EP3935954A1

  公开（公告）日：2022-01-12

  Provided is an application of the γ-quaternary ammonium butyrate compound shown in structural formula (I) or a racemate, a stereoisomer, a tautomer, a solvate, or a feed-acceptable salt thereof in the preparation of an animal feed additive, the compound being added to the daily feed of animals at a certain concentration ratio, and being capable of increasing the average daily weight gain of animals under the same food intake conditions, having no significant effect on the daily feed intake of the animals, and reducing the feed-to-meat ratio. The γ-quatemary ammonium butyrate compound or a racemate, a stereoisomer, a tautomer, a solvate, or a feed-acceptable salt thereof can effectively increase the rate of daily weight gain of the animals and improve the growth performance of the animals, having no side effects on the animals, being stable and safe, and improving the production efficiency of the breeding industry whilst ensuring the health of the animals.

  本发明提供了一种结构式（I）所示的γ-季铵丁酸盐化合物或其外消旋体、立体异构体、同分异构体、溶解物或饲料可接受盐在制备动物饲料添加剂中的应用，该化合物以一定的浓度比添加到动物的日常饲料中，能够在相同的采食量条件下提高动物的平均日增重，对动物的日采食量无明显影响，并降低料肉比。丁酸γ-迷迭香铵化合物或其外消旋体、立体异构体、同分异构体、溶解物或饲料可接受盐能有效提高动物的日增重率，改善动物的生长性能，对动物无副作用，稳定安全，在保证动物健康的同时提高养殖业的生产效率。