2-(Prop-2-en-1-ylidene)cyclopentan-1-one | 62716-61-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(Prop-2-en-1-ylidene)cyclopentan-1-one
• 英文别名: 2-prop-2-enylidenecyclopentan-1-one
• CAS: 62716-61-4
• 化学式: C₈H₁₀O
• 分子量: 122.16
• InChiKey: DLHCYZIPJQTERX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Chiral diphosphorus compounds and transition metal complexes thereof
  申请人：Knochel Paul

  公开号：US20050288523A1

  公开（公告）日：2005-12-29

  The present invention relates to chiral diphosphorus compounds and transition metal complexes thereof, to a process for preparing chiral diphosphorus compounds and oxides thereof, and transition metal complexes comprising the chiral diphosphorus compounds. In a further aspect, the invention relates to the use of the chiral diphosphorus compounds or transition metal complexes thereof in asymmetric syntheses.

  本发明涉及手性二膦化合物及其过渡金属配合物，涉及制备手性二膦化合物及其氧化物的方法，以及包含手性二膦化合物的过渡金属配合物。此外，该发明还涉及在不对称合成中使用手性二膦化合物或其过渡金属配合物。
• Process for producing 2-alkyl-2cyclopentenones
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20030109755A1

  公开（公告）日：2003-06-12

  Industrially advantageous processes for producing a 2-alkyl-2-cyclopentenone in high yields starting from a 2-(1-hydroxyalkyl)cyclopentanone or a 2-alkylidenecyclopentanone, which are obtainable from a cyclopentanone and a carbonyl compound. A 2-(1-hydroxyalkyl)cyclopentanone represented by the following general formula (1): 1 (wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 each independently represents hydrogen atom, an alkyl group having 1 to 10 carbon atoms which may have one or more substituents or an aromatic group which may have one or more substituents, and each of (1) R 6 or R 7 with R 3 and (2) R 6 or R 7 with R 4 or R 5 may be together combined to form a ring which may have a double bond) is subjected to dehydrative isomerization in the presence of a bromine compound and/or an iodine compound.

  从环戊酮和羰基化合物获得的2-(1-羟基烷基)环戊酮或2-烷基亚烯环戊酮，是从高产率开始生产2-烷基-2-环戊酮的工业上有利的过程。在以下一般式（1）中表示的2-(1-羟基烷基)环戊酮中（其中R1、R2、R3、R4、R5、R6和R7分别独立地表示氢原子、具有1至10个碳原子的烷基基团，可能具有一个或多个取代基或可能具有一个或多个取代基的芳香基团，且(1) R6或R7与R3和(2) R6或R7与R4或R5中的每一个可能结合在一起形成可能具有双键的环)在溴化合物和/或碘化合物的存在下进行脱水异构化。
• Process for the preparation of alkylidenecyclopentanone derivatives
  申请人：Chapuis Christian

  公开号：US20050187299A1

  公开（公告）日：2005-08-25

  The present invention relates to the field of organic synthesis and more particularly to a new process for the preparation of a compound of formula (I), in the form of any one of its isomers or a mixture thereof, wherein, more preferably, G represents a C═O group, R 1 represents a butyl group and R 2 represents a methyl group. The process of the invention involves an 2-(1-hydroxyalkyl)-cyclopent-2-en-1-one derivative, as starting material, which can be then converted into a compound of formula (I) by a process comprising a thermal rearrangement. The 2-alkylidene-3-oxo-cyclopentylacetate derivative and the 2-(1-hydroxyalkyl)-cyclopent-2-en-1-one derivative are also an object of the invention.

  本发明涉及有机合成领域，更特别地涉及一种制备式（I）化合物的新工艺，其形式为其任何一个异构体或其混合物，其中，更优选地，G代表C═O基团，R1代表丁基基团，R2代表甲基基团。本发明的工艺涉及以2-(1-羟基烷基)-环戊-2-烯-1-酮衍生物为起始材料，该起始材料可以通过包括热重排的过程转化为式（I）化合物。2-烷基亚甲基-3-氧代环戊基乙酸酯衍生物和2-(1-羟基烷基)-环戊-2-烯-1-酮衍生物也是本发明的对象。
• Process for producing 2-alkyl-2-cyclopentenones
  申请人：Takasago International Corporation

  公开号：EP1316541A1

  公开（公告）日：2003-06-04

  Industrially advantageous processes for producing a 2-alkyl-2-cyclopentenone in high yields starting from a 2-(1-hydroxyalkyl)cyclopentanone or a 2-alkylidenecyclopentanone, which are obtainable from a cyclopentanone and a carbonyl compound. A 2-(1-hydroxyalkyl)cyclopentanone represented by the following general formula (1): is subjected to dehydrative isomerization or a 2- alkylidenecyclopentanone represented by the following general formula (3): is isomerized. Both reactions take place in the presence of a bromine compound and/or an iodine compound. In the above formulae, R1-R7 have the meanings given in the description.

  以 2-(1-羟基烷基)环戊酮或 2-亚烷基环戊酮为原料，高产率生产 2-烷基-2-环戊酮的具有工业优势的工艺，这些环戊酮可从环戊酮和羰基化合物中获得。由以下通式 (1) 代表的 2-(1-羟基烷基)环戊酮： 的 2-(1-羟基烷基)环戊酮进行脱水异构化，或将以下通式(3)代表的 2-亚烷基环戊酮进行异构化： 进行异构化。这两种反应均在溴化合物和/或碘化合物存在下进行。 在上式中，R1-R7 具有说明中给出的含义。
• （Ｒ）−２−アルキルシクロペンタノンの製造方法
  申请人：長谷川香料株式会社

  公开号：JP2009034012A

  公开（公告）日：2009-02-19

  【課題】簡便、かつ安価な方法で、環境的にも負荷をかけることなく、高収率、高光学純度で、香料として有用な（Ｒ）−２−アルキルシクロペンタノンの製造方法を提供する。【解決手段】（Ｅ）−２−アルキリデンシクロペンタノンをブレビバクテリウム（Ｂｒｅｖｉｂａｃｔｅｒｉｕｍ）属に属する微生物の菌体またはその処理物と接触処理することを特徴とする（Ｒ）−２−アルキルシクロペンタノンの製造方法。【選択図】なし

  提供一种通过简单廉价的方法生产(R)-2-亚烷基环戊酮的方法，该方法产量高、光学纯度高，且不会对环境造成任何负担。 该方法的特征在于，(E)-2-亚烷基环戊酮是通过与属于 Brevibacterium 属的微生物或其处理产物接触来处理的。 -烷基环戊酮。 无。