1-[4-(Hydroxymethyl)phenyl]-2-(pyrrolidin-1-yl)propan-1-one | 646521-18-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[4-(Hydroxymethyl)phenyl]-2-(pyrrolidin-1-yl)propan-1-one
• 英文别名: 1-[4-(hydroxymethyl)phenyl]-2-pyrrolidin-1-ylpropan-1-one
• CAS: 646521-18-8
• 化学式: C₁₄H₁₉NO₂
• 分子量: 233.31
• InChiKey: MOCYRRGUYQCODZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

ADMET

代谢

HO-MPPP是锌33952402的一个已知人体代谢物。

HO-MPPP is a known human metabolite of zinc33952402.

来源:NORMAN Suspect List Exchange

文献信息

• IMMUNOASSAY FOR PYRROLIDINOPHENONES
  申请人：RANDOX LABORATORIES LIMITED

  公开号：US20160097783A1

  公开（公告）日：2016-04-07

  The current invention provides an improved immunoassay for the detection and determination of pyrrolidinophenone based designer drugs in hair and biological fluids (urine, blood, and oral fluid). The generic immunoassay is underpinned by novel, sub-family-specific antibodies, which display surprising sensitivity. The invention further describes substrates comprising an antibody that is specific to compounds of the pyrrolidinophenone family. Also described are the novel immunogens from which the antibodies are derived and kits incorporating the antibodies of the current invention.

  该发明提供了一种改进的免疫测定方法，用于检测和测定基于哌哆利啶酮类设计药物在头发和生物液体（尿液、血液和口腔液）中的含量。通用的免疫测定方法基于新颖的、亚家族特异性抗体，显示出惊人的灵敏度。该发明进一步描述了包含特异于哌哆利啶酮类化合物的抗体的底物。还描述了从中获得抗体的新颖免疫原以及包含本发明抗体的试剂盒。
• US9671415B2
  申请人：——

  公开号：US9671415B2

  公开（公告）日：2017-06-06