3-氧代丁基丙酸酯 | 457060-45-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3-氧代丁基丙酸酯
• 英文名称: 3-oxobutyl propionate
• 英文别名: 3-oxobutyl-propionate；2-Butanone, 4-(1-oxopropoxy)-；3-oxobutyl propanoate
• CAS: 457060-45-6
• 化学式: C₇H₁₂O₃
• mdl: MFCD18813395
• 分子量: 144.17
• InChiKey: JNKXOKDMAHMSFC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.714
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  丙酸丁酯 在 叔丁基过氧化氢 、 碘苯二乙酸 作用下， 以 水 、 乙腈 为溶剂， 反应 2.0h， 以56%的产率得到3-氧代丁基丙酸酯
  参考文献：
  名称：

  使用DIB / TBHP协议的未活化亚甲基CH的意外氧化

  摘要：

  原位生成的高价碘物质双（叔丁基过氧）碘苯用作过氧自由基源，可在非常温和的条件下将未反应的，较远且分离的烷基（环状或脂肪族）酯和酰胺氧化为相应的酮化合物情况。

  DOI：

  10.1021/ol2016466

文献信息

• Regio- and chemoselective rearrangement of terminal epoxides into methyl alkyl and aryl ketones
  作者：Yingying Tian、Eva Jürgens、Doris Kunz

  DOI：10.1039/c8cc06503a

  日期：——

  The development of the highly active pincer-type rhodium catalyst 2 for the nucleophilic Meinwald rearrangement of functionalised terminal epoxides into methyl ketones under mild conditions is presented. An excellent regio- and chemoselectivity is obtained for the first time for aryl oxiranes.

  提出了在温和条件下将官能化的末端环氧化物亲核性迈恩瓦尔德重排成甲基酮的高活性钳型铑催化剂2的开发。芳基环氧乙烷首次获得了优异的区域选择性和化学选择性。
• Nucleophilic Isomerization of Epoxides by Pincer‐Rhodium Catalysts: Activity Increase and Mechanistic Insights
  作者：Yingying Tian、Eva Jürgens、Katharina Mill、Ronja Jordan、Theo Maulbetsch、Doris Kunz

  DOI：10.1002/cctc.201900594

  日期：2019.8.21

  present the efficient isomerization of epoxides into methyl ketones with a novel pincer‐rhodium complex under very mild conditions. The catalyst system has an excellent functional group tolerance and a wide array of epoxides was tested. The corresponding methyl ketones were obtained in very high yields with excellent chemo‐ and regioselectivity. In addition, we investigated mechanistic details like the isomerization

  在此，我们介绍了在非常温和的条件下用新型的pin铑络合物将环氧化物有效异构化为甲基酮的方法。该催化剂体系具有出色的官能团耐受性，并测试了多种环氧化物。相应的甲基酮以很高的收率获得，具有出色的化学和区域选择性。此外，我们研究了催化剂异构化等机理细节，并获得了证据，表明环氧化物的亲核开环后，催化循环遵循β-氢化物消除-还原消除途径。
• Moulds With High Light Dispersion And High Light Transmission
  申请人：Rüdiger Claus

  公开号：US20080090958A1

  公开（公告）日：2008-04-17

  The present invention concerns a compound made of transparent thermoplastic resin, particularly polycarbonate, and a combination of inorganic particles on the basis of silicone dioxide and polymer particles on an acrylate basis with core-shell morphology, as well as moulds made from this compound.
• UV-PROTECTED POLYCARBONATE MOLDING MATERIALS EQUIPPED SO AS TO BE FLAME-RETARDANT AND HAVING A LOW MOLECULAR WEIGHT DECREASE
  申请人：Krauter Berit

  公开号：US20130221294A1

  公开（公告）日：2013-08-29

  The present invention relates to flameproofed, UV resistant polycarbonate moulding compositions with good melt stability and a high proportion of free, reactive UV absorbers, wherein the polycarbonate compositions comprise A) at least one polycarbonate with an average molecular weight M w of 18,000 to 40,000, B) at least one alkali or alkaline earth salt of an organic flame retardant consisting of diphenylsulfone, alkali or alkaline earth diphenylsulfone sulfonate and alkali or alkaline earth diphenylsulfone disulfonate, and C) one or more reactive UV absorbers, and wherein B) comprises diphenylsulfone in a proportion of 1.10 wt. % to 2.50 wt. %, based on the total mass of component B).
• FLAME-RESISTANT, UV-PROTECTED POLYCARBONATE MOULDING COMPOSITIONS OF LOW MOLECULAR WEIGHT DEGRADATION
  申请人：Krauter Berit

  公开号：US20130245165A1

  公开（公告）日：2013-09-19

  The present invention relates to flameproofed, UV-resistant polycarbonate moulding compositions having improved flame retardancy and a low incorporation of the UV absorber into the polymer chain and a resulting higher relative viscosity compared with the polycarbonates having increased incorporation of UV absorber, wherein the polycarbonate compositions comprise A) at least one polycarbonate having an average molecular weight M w of from 18,000 to 40,000 g/mol, B) one or more reactive UV absorbers and C) at least one alkali metal or alkaline earth metal salt of a fluorinated organic acid, and C) has a content of free sulfate of less than 0.007 wt. % and a content of free fluoride of less than 0.017 wt. %, in each case based on the weight of C).