8-Ethyl-4,4-bis-methoxymethyl-6-methyl-deca-6,7-dien-1-yne | 681272-66-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 8-Ethyl-4,4-bis-methoxymethyl-6-methyl-deca-6,7-dien-1-yne
• 英文别名: 8-Ethyl-4,4-bis(methoxymethyl)-6-methyldeca-6,7-dien-1-yne
• CAS: 681272-66-2
• 化学式: C₁₇H₂₈O₂
• 分子量: 264.408
• InChiKey: GREORTBJSLRRKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  8-Ethyl-4,4-bis-methoxymethyl-6-methyl-deca-6,7-dien-1-yne 在 platinum(II) chloride 作用下， 以 甲苯 为溶剂， 反应 32.0h， 生成 (1R,2S)-1-Ethyl-5,5-bis-methoxymethyl-2,7-dimethyl-2,4,5,6-tetrahydro-1H-indene 、 (1R,2R)-1-Ethyl-5,5-bis-methoxymethyl-2,7-dimethyl-2,4,5,6-tetrahydro-1H-indene
  参考文献：
  名称：

  PtCl₂-Catalyzed Cycloisomerizations of Allenynes

  摘要：

  The PtCl2-catalyzed cycloisomerization of allenyne systems has been examined. This process is a highly versatile tool for obtaining products that cannot be attainable with other metals. Simple adjustment of the allene or alkyne substitution can direct the reactivity in a selective manner and give birth to important carbocyclic frameworks (hydrindenes, cyclic vinylallenes, and trienes).

  DOI：

  10.1021/ja031892g

文献信息

• PtCl₂-Catalyzed Cycloisomerizations of Allenynes
  作者：Nicolas Cadran、Kevin Cariou、Gwénaëlle Hervé、Corinne Aubert、Louis Fensterbank、Max Malacria、José Marco-Contelles

  DOI：10.1021/ja031892g

  日期：2004.3.1

  The PtCl2-catalyzed cycloisomerization of allenyne systems has been examined. This process is a highly versatile tool for obtaining products that cannot be attainable with other metals. Simple adjustment of the allene or alkyne substitution can direct the reactivity in a selective manner and give birth to important carbocyclic frameworks (hydrindenes, cyclic vinylallenes, and trienes).