2-Ethoxy-1-phenyl-pent-4-en-1-one | 496861-00-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Ethoxy-1-phenyl-pent-4-en-1-one
• 英文别名: 2-Ethoxy-1-phenylpent-4-en-1-one；2-ethoxy-1-phenylpent-4-en-1-one
• CAS: 496861-00-8
• 化学式: C₁₃H₁₆O₂
• 分子量: 204.269
• InChiKey: GVXCOMNJCSKKJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,2-二乙氧基苯乙酮 、 烯丙基三甲基硅烷 在 三氟甲磺酸三甲基硅酯 、 1-正丁基-3-甲基咪唑三氟甲烷磺酸盐 作用下， 反应 23.0h， 以78%的产率得到2-Ethoxy-1-phenyl-pent-4-en-1-one
  参考文献：
  名称：

  Synthesis of Homoallyl Ethers via Allylation of Acetals in Ionic Liquids Catalyzed by Trimethylsilyl Trifluoromethanesulfonate

  摘要：

  The chemoselective allylation of acetals using allyltrimethylsilane in ionic liquids is catalyzed by TMS triflate (5.0-20.0 mol %). The reaction proceeds smoothly at room temperature to afford the corresponding homoallyl ether in good yield. Since the ionic liquids are easily recovered and recycled, they are a useful alternative to dichloromethane, which is the commonly used solvent for allylations.

  DOI：

  10.1021/ol0271739

文献信息

• Synthesis of Homoallyl Ethers via Allylation of Acetals in Ionic Liquids Catalyzed by Trimethylsilyl Trifluoromethanesulfonate
  作者：Herbert M. Zerth、Nicholas M. Leonard、Ram S. Mohan

  DOI：10.1021/ol0271739

  日期：2003.1.1

  The chemoselective allylation of acetals using allyltrimethylsilane in ionic liquids is catalyzed by TMS triflate (5.0-20.0 mol %). The reaction proceeds smoothly at room temperature to afford the corresponding homoallyl ether in good yield. Since the ionic liquids are easily recovered and recycled, they are a useful alternative to dichloromethane, which is the commonly used solvent for allylations.