4-Chloro-pentane-2,3-diol | 105827-11-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: 4-Chloro-pentane-2,3-diol
• 英文别名: 4-Chloropentane-2,3-diol；4-chloropentane-2,3-diol
• CAS: 105827-11-0
• 化学式: C₅H₁₁ClO₂
• 分子量: 138.594
• InChiKey: PGJUYAMPPKWBNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 Amberlyst 15 resin 、 lithium chloride 作用下， 以 乙腈 为溶剂， 生成 4-Chloro-pentane-2,3-diol
  参考文献：
  名称：

  An Easy Procedure for the Highly Regioselective Conversion of Epoxides to Halohydrins

  摘要：

  Several epoxides and epoxy alcohols have been opened to the corresponding halohydrins by lithium halides with Amberlyst in CH3CN at room temperature : the reaction proceeds in quantitative yields with high degree of regioselectivity.

  DOI：

  10.1080/00397919208021317

文献信息

• An Easy Procedure for the Highly Regioselective Conversion of Epoxides to Halohydrins
  作者：Bonini、Giuliano、Righi、Rossi

  DOI：10.1080/00397919208021317

  日期：1992.7

  Several epoxides and epoxy alcohols have been opened to the corresponding halohydrins by lithium halides with Amberlyst in CH3CN at room temperature : the reaction proceeds in quantitative yields with high degree of regioselectivity.