1,1'-(4-Hydroxy-1,2-phenylene)di(ethan-1-one) | 90464-79-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1'-(4-Hydroxy-1,2-phenylene)di(ethan-1-one)
• 英文别名: 1-(2-acetyl-4-hydroxyphenyl)ethanone
• CAS: 90464-79-2
• 化学式: C₁₀H₁₀O₃
• 分子量: 178.18
• InChiKey: KJTIQYSFSYOVFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• DITHIOL MUCOLYTIC AGENTS
  申请人：Johnson Michael R.

  公开号：US20150056305A1

  公开（公告）日：2015-02-26

  Provided are dithiol mucolytic agents. These agents increase the liquefaction of mucus in a patient with excessive mucus or mucus with increased viscoelastic, cohesive, or adhesive properties. Also provided are a variety of methods of treatment using these inventive mucolytic agents.

  提供了二硫醚粘液溶解剂。这些剂增加了病人体内过多黏液或具有增加的粘弹性、黏着性或粘附性的黏液的液化。还提供了使用这些创新黏液溶解剂的各种治疗方法。
• NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS
  申请人：PARION SCIENCES, INC.

  公开号：US20160318861A1

  公开（公告）日：2016-11-03

  Provided are mucolytic compounds that are more effective, and/or absorbed less rapidly from mucosal surfaces, and/or are better tolerated as compared to N-acetylcysteine (NAC) and DTT. The compounds are represented by compounds of Formula I which embrace structures (Ia)-(Ib): where the structural variables are as defined herein.
• US9346753B2
  申请人：——

  公开号：US9346753B2

  公开（公告）日：2016-05-24
• US9963427B2
  申请人：——

  公开号：US9963427B2

  公开（公告）日：2018-05-08