| 1209493-96-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• CAS: 1209493-96-8
• 化学式: C₁₈H₂₄N₈O₈
• 分子量: 480.437
• InChiKey: LFLBQIAVYYGYKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.75
• 重原子数：
  34.0
• 可旋转键数：
  8.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  173.1
• 氢给体数：
  0.0
• 氢受体数：
  16.0

反应信息

• 作为产物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Cyanomethylamines and azidomethylamines: new general methods of the synthesis and transformations

  摘要：

  Simple and efficient methods have been developed to obtain cyanomethylamines and azidomethylamines using reactions of methoxymethylamines with TMSCN and TMSN3, respectively. In the case of dimethylformamide dimethylacetal, only one MeO group was substituted with CN, and an unexpected direction of the subsequent azidation was found. Adducts of azidomethylamines with DMAD were studied, and the base-catalyzed isomerization of symmetric triazoles into non-symmetric ones was revealed.

  DOI：

  10.1016/j.mencom.2009.09.018