2-hydroxy-5-(3-hydroxypropyl)-3-methylcyclopent-2-enone | 1187852-46-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxy-5-(3-hydroxypropyl)-3-methylcyclopent-2-enone
• 英文别名: 2-Hydroxy-5-(3-hydroxypropyl)-3-methylcyclopent-2-en-1-one
• CAS: 1187852-46-5
• 化学式: C₉H₁₄O₃
• 分子量: 170.208
• InChiKey: CKYTUAVATIUXTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-(5,6-dihydro-4H-pyran-2-yl)-2-methyl-propenone 在 scandium tris(dodecyl sulfate) 、 水 作用下， 反应 24.0h， 以92%的产率得到2-hydroxy-5-(3-hydroxypropyl)-3-methylcyclopent-2-enone
  参考文献：
  名称：

  Nazarov-type Reactions in Water

  摘要：

  AbstractDifferent in water! We have developed Nazarov‐type reactions in water. Different reaction courses compared with those in organic solvents are observed in water. In the presence of a scandium based, surfactant‐type catalyst, water‐trapping products are obtained exclusively. The results presented are unprecedented and provide a valuable extension to information available regarding organic reactions in water.magnified image

  DOI：

  10.1002/asia.200800461

文献信息

• Nazarov-type Reactions in Water
  作者：Masaya Kokubo、Shū Kobayashi

  DOI：10.1002/asia.200800461

  日期：2009.4.6

  AbstractDifferent in water! We have developed Nazarov‐type reactions in water. Different reaction courses compared with those in organic solvents are observed in water. In the presence of a scandium based, surfactant‐type catalyst, water‐trapping products are obtained exclusively. The results presented are unprecedented and provide a valuable extension to information available regarding organic reactions in water.magnified image