(3S,5S,5aR,6R,7S,8S,8aR)-decahydrocyclopenta[b]azepine-3,4,5,6,7,8-hexaol | 1491933-64-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉类
• 英文名称: (3S,5S,5aR,6R,7S,8S,8aR)-decahydrocyclopenta[b]azepine-3,4,5,6,7,8-hexaol
• 英文别名: (3S,4R,5S,5aR,6R,7S,8S,8aR)-1,2,3,4,5,5a,6,7,8,8a-decahydrocyclopenta[b]azepine-3,4,5,6,7,8-hexol
• CAS: 1491933-64-2
• 化学式: C₉H₁₇NO₆
• 分子量: 235.237
• InChiKey: LWLXGAVESPVOKH-OKYDTINISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  133
• 氢给体数：
  7
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  (3S,5S,5aR,6R,7S,8S,8aR)-6,7,8-trisbenzyloxydecahydrocyclopenta[b]azepine-3,4,5-triol 在 氨 、 sodium 作用下， 以 四氢呋喃 为溶剂， 反应 5.0h， 以80%的产率得到(3S,5S,5aR,6R,7S,8S,8aR)-decahydrocyclopenta[b]azepine-3,4,5,6,7,8-hexaol
  参考文献：
  名称：

  Synthesis of polyhydroxylated aza-bicyclic compounds from sugar allyltins

  摘要：

  Highly functionalized polyhydroxylated dienoaldehyde, readily obtained from allyltin and D-glucose, served as a convenient precursor for a variety of configurationally different aza-bicyclic polyols. Such derivatives were deprotected and the activity of these free compounds against glycosidases was also tested. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2013.09.016