3-Hydroxy-2,4-hexanedione | 177483-75-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Hydroxy-2,4-hexanedione
• 英文别名: 3-hydroxyhexane-2,4-dione
• CAS: 177483-75-9
• 化学式: C₆H₁₀O₃
• 分子量: 130.14
• InChiKey: YZRCADLLOAXRLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• METHIONINE PRODUCTION
  申请人：Evonik Degussa GmbH

  公开号：EP3095868A1

  公开（公告）日：2016-11-23

  The present invention relates to a microbial cell capable of producing at least one acetylhomoserine from 4-acetyl-butyric acid and/or ester thereof, wherein the cell is genetically modified to comprise - at least a first genetic mutation that increases the expression relative to the wild type cell of an enzyme E1 capable of catalysing the hydroxylation of 4-acetyl-butyric acid and/or ester thereof to an alpha-hydroxy acetyl butanone, and - at least a second genetic mutation that increases the expression relative to the wild type cell of enzyme E2 capable of catalysing the amination of the alpha-hydroxy acetyl butanone to the acetylhomoserine.

  本发明涉及一种能从 4-乙酰丁酸和/或其酯生产至少一种乙酰高丝氨酸的微生物细胞，其中该细胞经基因修饰后包括 - 至少第一个基因突变，相对于野生型细胞，该突变增加了能够催化 4-乙酰丁酸和/或其酯羟基化为α-羟基乙酰丁酮的酶 E1 的表达，以及 - 至少第二种基因突变，相对于野生型细胞，增加了能催化α-羟基乙酰丁酮氨化为乙酰高丝氨酸的酶 E2 的表达量。
• [EN] HYDROPHILIC MEMBER AND FORMING METHOD OF THE SAME<br/>[FR] ELÉMENT HYDROPHILE ET SON PROCÉDÉ DE FABRICATION
  申请人：FUJIFILM CORP

  公开号：WO2013039252A1

  公开（公告）日：2013-03-21

  A hydrophilic member includes a base material; and a layer containing a hydrophilic material (1) and an oligomer or polymer (2), the layer is a composition gradient layer in which a composition of (1) and (2) continuously changes in a thickness direction of the layer in such a manner that a ratio of (1) becomes large, whereas a ratio of (2) becomes small, from the nearest side to the base material toward the farthest side to the base material, the hydrophilic material (1) is a hydrophilic material containing a hydrolyzable silyl group-containing hydrophilic polymer, the polymer having at least one hydrolyzable silyl group represented by the formula (a) as defined herein at a main chain end or side chain of a molecule thereof and having at least one hydrophilic group in the molecule, and the oligomer or polymer (2) is different from the hydrophilic polymer (1).
• [EN] METHIONINE PRODUCTION<br/>[FR] PRODUCTION DE MÉTHIONINE
  申请人：EVONIK DEGUSSA GMBH

  公开号：WO2016184663A1

  公开（公告）日：2016-11-24

  The present invention relates to a microbial cell capable of producing at least one acetylhomoserine from 4-acetyl-butyric acid and/or ester thereof, wherein the cell is genetically modified to comprise -at least a first genetic mutation that increases the expression relative to the wild type cell of an enzyme E1 capable of catalysing the hydroxylation of 4-acetyl-butyric acid and/or ester thereof to an alpha-hydroxy acetyl butanone, and -at least a second genetic mutation that increases the expression relative to the wild type cell of enzyme E2 capable of catalysing the amination of the alpha-hydroxy acetyl butanone to the acetylhomoserine.