3-Methoxypyridin-1-ium-1-amine;iodide | 28460-32-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Methoxypyridin-1-ium-1-amine;iodide
• CAS: 28460-32-4
• 化学式: C6H9IN2O
• 分子量: 252.05
• InChiKey: QCAFZZNERWCUMW-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  39.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PYRAZOLOPYRIDINE INHIBITORS OF C-JUN-N-TERMINAL KINASES AND USES THEREOF
  申请人：Dana-Farber Cancer Institute, Inc.

  公开号：EP3893879A1

  公开（公告）日：2021-10-20
• [EN] PYRAZOLOPYRIDINE INHIBITORS OF C-JUN-N-TERMINAL KINASES AND USES THEREOF<br/>[FR] INHIBITEURS DE PYRAZOLOPYRIDINE DE KINASES C-JUN N-TERMINALES ET LEURS UTILISATIONS
  申请人：DANA FARBER CANCER INST INC

  公开号：WO2020123925A1

  公开（公告）日：2020-06-18

  Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopologues, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing diseases (e.g., proliferative diseases (e.g., cancers and benign neoplasms), inflammatory diseases (e.g., rheumatoid arthritis), and vascular diseases (e.g., atherosclerosis) in a subject. Provided are methods of inhibiting a INK (e.g., JNK1, JNK2, or JNK3) in a subject.