2-氰甲醇N-甲基-N-苯基二硫代氨基甲酸酯 | 76926-16-4

• 物质功能分类: 生物化工 - 生化试剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-氰甲醇N-甲基-N-苯基二硫代氨基甲酸酯
• 中文别名: 2-氰基甲基-N-甲基-N-苯基二硫代氨基甲酸酯；N-甲基-N-苯基二硫代氨基甲酸氰甲基酯；甲基(苯基)氨基二硫代甲酸氰甲酯
• 英文名称: Cyanomethyl methyl(phenyl)carbamodithioate
• 英文别名: cyanomethyl N-methyl-N-phenylcarbamodithioate
• CAS: 76926-16-4
• 化学式: C₁₀H₁₀N₂S₂
• mdl: MFCD16038113
• 分子量: 222.3
• InChiKey: FYACMHCOSCVNHO-UHFFFAOYSA-N

物化性质

• 熔点：
  88-92°C
• 沸点：
  347.1±44.0 °C(Predicted)
• 密度：
  1.286±0.06 g/cm3(Predicted)
• 溶解度：
  DMSO（少量）、甲醇（少量）

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  84.4
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• WGK Germany：
  3
• 危险性防范说明：
  P261,P272,P280,P302+P352,P333+P313,P363,P501
• 危险性描述：
  H317

制备方法与用途

用途 

可控自由基聚合的RAFT试剂；尤其适用于乙烯基酯和乙烯基酰胺单体的聚合。链转移试剂(CTA)

文献信息

• Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

  公开号：US20200353090A1

  公开（公告）日：2020-11-12

  The invention relates to new prodrugs of active molecules. These prodrugs allow, in particular, the subcutaneous or intramuscular administration of active molecules of which the subcutaneous or intramuscular administration is problematic or impossible, in particular because of the toxicity at the injection site. The prodrugs according to the invention comprise an active ingredient, covalently linked with a polymer chain, preferably a hydrophilic and/or thermosensitive polymer chain. The invention relates, in particular, to polymeric prodrugs comprising a polymer chain formed at least in part by acrylamide monomer or one of its derivatives, the polymer comprising a proximal part and a terminal part; a first pharmaceutically active molecule covalently coupled to the proximal part of the polymer; possibly a second pharmaceutically active molecule covalently coupled to the terminal part of the polymer.

  该发明涉及新型活性分子的前药。这些前药允许特别是将活性分子皮下或肌肉内注射，而这些活性分子的皮下或肌肉内注射由于在注射部位的毒性而具有问题或不可能，特别是由于在注射部位的毒性。根据本发明的前药包括一种活性成分，与一根聚合物链共价连接，优选为一种亲水性和/或热敏感性聚合物链。该发明特别涉及包括由丙烯酰胺单体或其衍生物之一至少部分形成的聚合物链的聚合物前药，该聚合物包括一个近端部分和一个末端部分；第一种药用活性分子共价结合到聚合物的近端部分；可能第二种药用活性分子共价结合到聚合物的末端部分。
• Polymerizable sulfonamide compounds and polymers thereof
  申请人：Massachusetts Institute of Technology

  公开号：US11155674B2

  公开（公告）日：2021-10-26

  Methods, compositions, reagents, and systems that allow for the preparation and utilization of sulfonamide salt polymer electrolytes are disclosed herein. Methods and reagents to prepare sulfonamide salt monomers are also disclosed herein. The sulfonamide salt polymer electrolytes can be used as components in energy storage devices, conductive materials, electrochemical cells, gels, adhesives, and drug delivery vehicles.

  本文公开了允许制备和利用磺胺盐聚合物电解质的方法、组合物、试剂和系统。本文还公开了制备磺胺盐单体的方法和试剂。磺胺盐聚合物电解质可用作能量存储设备、导电材料、电化学电池、凝胶、粘合剂和药物输送载体中的组件。
• [EN] ALL PURPOSE RAFT AGENT<br/>[FR] AGENT RAFT POLYVALENT
  申请人：COMMW SCIENT IND RES ORG

  公开号：WO2016054689A1

  公开（公告）日：2016-04-14

  The present invention relates to a RAFT agent of formula (I) where R1, R2 and R3 are each independently selected from H and optionally substituted alkyl.

  本发明涉及一种公式（I）的RAFT试剂，其中R1、R2和R3分别独立地选择自H和可选取代烷基。
• CONDUCTIVE TRANSPARENT ADHESIVE COMPOSITION AND ADHESIVE PREPARED BY USING THE SAME
  申请人：Kim Eun Kyoung

  公开号：US20130234076A1

  公开（公告）日：2013-09-12

  An electroconductive transparent adhesive composition containing a transparent adhesive monomer, any one electroconductive mesoporous filler selected from the group consisting of porous carbon, an electroconductive polymer and combinations thereof, and a polymerization initiator, and an electroconductive transparent adhesive produced using the composition are provided. The electroconductive transparent adhesive composition is less expensive and highly economically efficient, and has excellent electrical conductivity and transparency, and has excellent mechanical strength. Thus, the electroconductive transparent adhesive composition can be used in a variety of electrical and electronic applications such as touch screens, displays, and electronic devices.

  提供了一种电导透明胶粘剂组合物，包含透明胶粘单体、任选自多孔碳、电导聚合物和两者的组合的任意一种电导介孔填料和聚合引发剂，以及使用该组合物制备的电导透明胶粘剂。该电导透明胶粘剂组合物价格较低，经济效益高，具有优异的电导性和透明度，以及出色的机械强度。因此，电导透明胶粘剂组合物可用于各种电气和电子应用，如触摸屏、显示器和电子设备。
• BLOCK COPOLYMER CONTAINING CATECHOL SEGMENT, INORGANIC NANOPARTICLES COATED BY SAID BLOCK COPOLYMER, METHOD FOR PRODUCING BLOCK COPOLYMER CONTAINING CATECHOL SEGMENT, AND METHOD FOR PRODUCING INORGANIC NANOPARTICLES COATED BY SAID BLOCK COPOLYMER
  申请人：Japan Science and Technology Agency

  公开号：EP3112387A1

  公开（公告）日：2017-01-04

  Provided is a block copolymer that makes it possible to produce inorganic nanoparticles that can be dispersed in an organic solvent, the inorganic nanoparticles being of uniform size and a reducing agent not having to be used. A block copolymer including a catechol segment represented by formula (1).

  本发明提供了一种嵌段共聚物，该共聚物可生产出分散在有机溶剂中的无机纳米粒子，无机纳米粒子大小均匀，且无需使用还原剂。 一种嵌段共聚物，包括由式（1）表示的邻苯二酚段。