5-Bromo-6-(4-bromoanilino)-2-ethyl-1,3-benzoxazole-4,7-dione | 1190758-56-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Bromo-6-(4-bromoanilino)-2-ethyl-1,3-benzoxazole-4,7-dione
• CAS: 1190758-56-5
• 化学式: C₁₅H₁₀Br₂N₂O₃
• 分子量: 426.064
• InChiKey: ZAQAWFYVXIFRRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  72.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  5,6-dibromo-2-ethylbenzo[d]oxazole-4,7-dione 、 4-溴苯胺 以 乙醇 为溶剂， 反应 5.0h， 生成 5-Bromo-6-(4-bromoanilino)-2-ethyl-1,3-benzoxazole-4,7-dione
  参考文献：
  名称：

  Synthesis and antifungal activity of benzo[d]oxazole-4,7-diones

  摘要：

  Benzo[d]oxazole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that benzo[d]oxazole-4,7-diones would be potent antifungal agents. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2009.08.062

文献信息

• Synthesis and antifungal activity of benzo[d]oxazole-4,7-diones
  作者：Chung-Kyu Ryu、Ra-Young Lee、Na Young Kim、Yang Hui Kim、Ae Li Song

  DOI：10.1016/j.bmcl.2009.08.062

  日期：2009.10

  Benzo[d]oxazole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that benzo[d]oxazole-4,7-diones would be potent antifungal agents. (C) 2009 Elsevier Ltd. All rights reserved.