3-acetoxy-chalcone | 133371-93-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 3-acetoxy-chalcone
• 英文别名: 3-Acetoxy-chalkon；[3-[(E)-3-oxo-3-phenylprop-1-enyl]phenyl] acetate
• CAS: 133371-93-4
• 化学式: C₁₇H₁₄O₃
• 分子量: 266.296
• InChiKey: FQNHHOSVKIICSE-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-acetoxy-chalcone 在 二硫化碳 、 溴 作用下， 生成 3-(3-acetoxy-phenyl)-2,3-dibromo-1-phenyl-propan-1-one
  参考文献：
  名称：

  Bablich; v. Kostanecki, Chemische Berichte, 1896, vol. 29, p. 235

  摘要：

  DOI：

文献信息

• A Simple, Efficient, and Green Procedure for the 1,4-Addition of Thiols to Conjugated Alkenes and Alkynes Catalyzed by Sodium Acetate in Aqueous Medium
  作者：Brindaban C. Ranu、Tanmay Mandal

  DOI：10.1071/ch06455

  日期：——

  A benign and inexpensive salt, sodium acetate, efficiently catalyzes 1,4-addition of thiols to a variety of conjugated alkenes such as α,β-unsaturated ketones, aldehydes, carboxylic esters, nitriles, nitro compounds, and chalcones in aqueous THF. The reactions are clean, fast, and high yielding.

  一种温和且廉价的盐乙酸钠可在 THF 水溶液中有效催化硫醇与各种共轭烯烃（例如 α,β-不饱和酮、醛、羧酸酯、腈、硝基化合物和查耳酮）的 1,4-加成反应。反应干净、快速且产率高。
• Catalysis by ionic liquid: a simple, green and efficient procedure for the Michael addition of thiols and thiophosphate to conjugated alkenes in ionic liquid, [pmIm]Br
  作者：Brindaban C Ranu、Suvendu S Dey

  DOI：10.1016/j.tet.2004.03.052

  日期：2004.5

  A room temperature ionic liquid, 1-pentyl-3-methylimidazolium bromide, [pmIm]Br efficiently catalyzes Michael addition of thiols and diethyl dithiophosphate to a variety of conjugated alkenes such as alpha,beta-unsaturated carbonyl compounds, carboxylic esters, nitriles and chalcones without requiring any other organic solvent and catalyst. The ionic liquid can be recycled for subsequent reactions without any appreciable loss of efficiency. (C) 2004 Elsevier Ltd. All rights reserved.