N,N-dichloro 4-amino-4-phosphono-butyric acid | 903893-57-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: N,N-dichloro 4-amino-4-phosphono-butyric acid
• 英文别名: 4-(Dichloroamino)-4-phosphonobutanoic acid
• CAS: 903893-57-2
• 化学式: C₄H₈Cl₂NO₅P
• 分子量: 251.991
• InChiKey: DWYLYZGWBIVRGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  98.1
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN<br/>[FR] MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DE LA DOULEUR
  申请人：HELLER ADAM

  公开号：WO2010017405A1

  公开（公告）日：2010-02-11

  The invention features methods, kits, and compositions for the treatment of pain.

  本发明涉及用于治疗疼痛的方法、试剂盒和组合物。
• ANTIMICROBIAL GEL FORMULATIONS
  申请人：Wang Lu

  公开号：US20100076089A1

  公开（公告）日：2010-03-25

  Disclosed herein are formulations comprising an N-halogenated or N,N-dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 25° C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.

  本文揭示了一种配方，其中包含一种N-卤代或N,N-二卤代胺化合物分散在可水肿胀的聚合物中，其中该化合物在大约25°C下稳定90％，至少30天。还揭示了使用这种配方治疗或预防由细菌、微生物、孢子、真菌或病毒活性引起的感染的方法。
• N,N-dihalogenated amino acids and derivatives
  申请人：NovaBay Pharmaceuticals, Inc.

  公开号：EP2725008A1

  公开（公告）日：2014-04-30

  The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

  本发明涉及活性杀菌剂、抗菌剂、抗感染剂、抗菌剂、杀孢子剂、消毒剂、抗真菌剂和抗病毒剂化合物和组合物，以及这些组合物在治疗中的新用途。本说明书还介绍了新化合物和组合物的使用方法。本说明书进一步介绍了制备这些化合物的方法。
• N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them
  申请人：Najafi Ramin

  公开号：US20060247209A1

  公开（公告）日：2006-11-02

  The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

  本发明涉及活性杀菌剂、抗菌剂、抗感染剂、抗菌剂、杀孢子剂、消毒剂、抗真菌剂和抗病毒剂化合物和组合物，以及这些组合物在治疗中的新用途。本说明书还介绍了新化合物和组合物的使用方法。本说明书进一步介绍了制备这些化合物的方法。
• N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES
  申请人：NovaCal Pharmaceuticals, Inc.

  公开号：EP1656095A2

  公开（公告）日：2006-05-17