2-allyl-isothiazol-3-one | 51722-90-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-allyl-isothiazol-3-one
• 英文别名: 2-allyl-3-isothiazolone；2-Prop-2-enyl-1,2-thiazol-3-one
• CAS: 51722-90-8
• 化学式: C₆H₇NOS
• 分子量: 141.194
• InChiKey: MBMBJLJKQQAHPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异噻唑-3-酮 、 3-溴丙烯 、 sodium methylate 生成 2-allyl-isothiazol-3-one
  参考文献：
  名称：

  LEWIS, S. N.;MILLER, G. A.;LAW, A. B.

  摘要：

  DOI：

文献信息

• Preparation of N-Substituted Isothiazolinone Derivatives
  申请人：Jin Yuechun

  公开号：US20080227986A1

  公开（公告）日：2008-09-18

  Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced.

  提供了一种制备具有通式（I）的N-取代异噻唑酮衍生物的过程，包括在无溶剂的情况下，将通式（II）的N-取代3-巯基丙酰胺或通式（III）的N，N′-双取代3,3′-二硫代丙酰胺与亚硫酰氯反应。还提供了一种制备具有通式（III）的化合物的过程，包括在甲醇溶剂中，将通式（IV）的甲酯与通式（V）的胺反应。由于本发明过程中没有使用额外的溶剂，可以降低制造成本和对环境的污染。
• Process for treating water
  申请人：Innovative Medical Services

  公开号：US20030178374A1

  公开（公告）日：2003-09-25

  A process is disclosed for treating impure water by introducing a solution of electrolyticially generated silver citrate into the impure water wherein the silver is electrolytically generated in a solution of citric acid and water.

  公开了一种处理不纯水的过程，通过将电解生成的柠檬酸银溶液引入不纯水中处理，其中银在柠檬酸和水的溶液中被电解生成。
• Disinfectant and method of making
  申请人：Arata B. Andrew

  公开号：US20050274624A1

  公开（公告）日：2005-12-15

  A non-toxic environmentally friendly aqueous disinfectant is disclosed for specific use as prevention against contamination by potentially pathogenic bacteria and virus. The aqueous disinfectant is formulated by electrolytically generating silver ions in water in combination with a citric acid. The aqueous disinfectant may include a suitable alcohol and/or a detergent. The aqueous disinfectant has been shown to be very effective at eliminating standard indicator organisms such as staphylococcus aureus, salmonella cholerasuis and pseudomonas aeruginosa.

  本发明揭示了一种无毒、环保的水性消毒剂，特别用于预防可能病原菌和病毒的污染。该水性消毒剂是通过在水中电解生成银离子与柠檬酸的组合来制备的。该水性消毒剂可以包括适当的酒精和/或洗涤剂。该水性消毒剂已被证明在消灭金黄色葡萄球菌、霍乱沙门氏菌和铜绿假单胞菌等标准指示生物方面非常有效。
• PROCESS FOR TREATING WATER
  申请人：ARATA Andrew B.

  公开号：US20100012593A1

  公开（公告）日：2010-01-21

  A process is disclosed for treating impure water by introducing a solution of electrolyticially generated silver citrate into the impure water wherein the silver is electrolytically generated in a solution of citric acid and water.

  公开了一种处理不纯水的方法，该方法通过将电解生成的柠檬酸银溶液引入不纯水中进行处理，其中银是在柠檬酸和水的溶液中电解生成的。
• PREPARATION OF N-SUBSTITUTED ISOTHIAZOLINONE DERIVATIVES
  申请人：Jin Yuechun

  公开号：US20110112327A1

  公开（公告）日：2011-05-12

  Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced.

  提供了一种制备具有通式(I)的N-取代异噻唑啉衍生物的过程，包括在无溶剂的情况下将通式(II)的N-取代3-巯基丙酰胺或通式(III)的N,N'-双取代3,3'-二硫代丙酰胺与亚磺酰氯反应。还提供了一种制备具有通式(III)的化合物的过程，包括在甲醇溶剂中将通式(IV)的甲酯与通式(V)的胺反应。由于本发明过程中未使用任何添加溶剂，因此可以降低制造成本和对环境的污染。