3,3'-dimethoxy-1,1'-sulfanediyl-bis-propan-2-ol | 20142-84-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,3'-dimethoxy-1,1'-sulfanediyl-bis-propan-2-ol
• 英文别名: 1-(2-Hydroxy-3-methoxypropyl)sulfanyl-3-methoxypropan-2-ol
• CAS: 20142-84-1
• 化学式: C₈H₁₈O₄S
• 分子量: 210.295
• InChiKey: HWNRTWBJWIMHCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  84.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• METHOD FOR PRODUCING ORGANIC SULFUR COMPOUND, CARRIER, METHOD FOR PRODUCING SAID CARRIER, LIGAND-IMMOBILIZING CARRIER, CHROMATOGRAPHY COLUMN, AND METHOD FOR DETECTING OR ISOLATING TARGET SUBSTANCE
  申请人：JSR CORPORATION

  公开号：US20220001358A1

  公开（公告）日：2022-01-06

  Provided is a carrier which has excellent pressure resistance, and even when a protein ligand is not immobilized thereon, has a high dynamic binding capacity to a target substance, and has a high performance of separating a target substance from a biological sample. The carrier includes a polymer having a crosslinked structure containing a divalent group represented by the following Formula (1): wherein R 1 to R 4 independently represent a single bond or a divalent hydrocarbon group, R 5 and R 6 independently represent a hydrogen atom or a hydrocarbon group, X represents a thio group, a sulfinyl group, a sulfonyl group, an oxy group, >N(—R 31 ), >Si(—R 32 ) 2 , >P(—R 33 ), >P(═O)(—R 34 ), >B(—R 35 ), or >C(—R 36 ) 2 (R 31 to R 36 independently represent a hydrogen atom or hydrocarbon group), and * represents a bond, with a proviso that when both R 1 and R 3 are a divalent hydrocarbon group, R 1 and R 3 may form a ring together with an adjacent carbon atom, and when both R 2 and R 4 are a divalent hydrocarbon group, R 2 and R 4 may form a ring together with an adjacent carbon atom.

  提供了一种载体，具有出色的耐压性，并且即使没有蛋白质配体固定在其上，也具有高动态结合能力，能够高效地从生物样品中分离目标物质。该载体包括具有交联结构的聚合物，其中包含以下式（1）所表示的二价基团： 其中，R1至R4独立地表示单键或二价碳氢基团，R5和R6独立地表示氢原子或碳氢基团，X表示硫基、亚砜基、磺酰基、氧基、>N(—R31)、>Si(—R32)2、>P(—R33)、>P(═O)(—R34)、>B(—R35)或>C(—R36)2（其中，R31至R36独立地表示氢原子或碳氢基团），*表示键，但当R1和R3均为二价碳氢基团时，R1和R3可以与相邻的碳原子一起形成环；当R2和R4均为二价碳氢基团时，R2和R4可以与相邻的碳原子一起形成环。