L-tyrosine*β-cyclodextrin | 103928-89-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: L-tyrosine*β-cyclodextrin
• CAS: 103928-89-8
• 化学式: C₉H₁₁NO₃*C₄₂H₇₀O₃₅
• 分子量: 1316.19
• InChiKey: ZOJNXOZTGNKAKX-CYBIHCENSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -14.88
• 重原子数：
  90.0
• 可旋转键数：
  10.0
• 环数：
  22.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  637.6
• 氢给体数：
  24.0
• 氢受体数：
  38.0

反应信息

• 作为产物：
  描述：

  L-酪氨酸 、 β-环糊精 以 水 为溶剂， 生成 L-tyrosine*β-cyclodextrin
  参考文献：
  名称：

  Host–guest interaction of l-tyrosine with β-cyclodextrin

  摘要：

  The inclusion complexes of beta-cyclodextrin (beta-CD) with L-tyrosine (L-TYN) were investigated by using spectrophotometers. The absorption and fluorescence enhancement occurs with beta-CD and L-TYN forms 1: 1 inclusion complex. The unusual blue shift of hydroxyl ion in the Chi-CD medium confirms OH groups present in the interior part of the beta-CD cavity and -COOH group present in the upper part of the beta-CD cavity. A mechanism is proposed to explain inclusion process. The inclusion interaction was examined and the thermodynamic parameters of inclusion process Delta G, Delta H and Delta S were determined. The results indicated that the inclusion process was an exergonic and spontaneous process. Stable solid inclusion complexes were established and characterized by FT-IR, scanning electron microscope (SEM) methods. (C) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.10.054