5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,6-dihydro-2H-pyran | 916168-55-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,6-dihydro-2H-pyran
• 英文别名: 5-(4-ethoxy-2,3-difluorophenyl)-2-pentyl-3,6-dihydro-2H-pyran
• CAS: 916168-55-3
• 化学式: C₁₈H₂₄F₂O₂
• 分子量: 310.384
• InChiKey: HYAPNYFSEUQSLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,6-dihydro-2H-pyran 、 5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,4-dihydro-2H-pyran 在 5% palladium over charcoal 氢气 作用下， 以 四氢呋喃 为溶剂， 50.0 ℃ 、500.01 kPa 条件下， 以34%的产率得到5-(4-ethoxy-2,3-difluoro-phenyl)-2-trans-pentyl-tetrahydropyran
  参考文献：
  名称：

  WO2006/125550

  摘要：

  公开号：
• 作为产物：
  描述：

  3-(4-ethoxy-2,3-difluoro-phenyl)-6-pentyl-tetrahydropyran-3-ol 在 吡啶 、 氯化亚砜 作用下， 生成 5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,6-dihydro-2H-pyran 、 5-(4-ethoxy-2,3-difluoro-phenyl)-2-pentyl-3,4-dihydro-2H-pyran
  参考文献：
  名称：

  WO2006/125550

  摘要：

  公开号：

文献信息

• LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL DIMMER ELEMENT
  申请人：JNC Corporation

  公开号：EP3553154A1

  公开（公告）日：2019-10-16

  Provided are: a liquid crystal composite which is suited to dimming, and which contains a liquid crystal composition satisfying at least one of characteristics including a high upper limit temperature, a low lower limit temperature, a low viscosity, a high optical anisotropy, and a high negative dielectric anisotropy, or having an appropriate balance between at least two of these characteristics; and a liquid crystal dimmer element having the liquid crystal composite. The liquid crystal composite comprises a polymer and a liquid crystal composition containing a specific compound having a high negative dielectric anisotropy. The liquid crystal composite may further comprise a specific compound having a high upper limit temperature or a low lower limit temperature.

  本文提供了：一种适合调光的液晶复合材料，它含有一种液晶组合物，该液晶组合物满足包括高上限温度、低下限温度、低粘度、高光学各向异性和高负介电各向异性在内的至少一种特性，或在至少两种这些特性之间具有适当的平衡；以及一种具有该液晶复合材料的液晶调光元件。液晶复合材料包括聚合物和液晶组合物，其中液晶组合物含有具有高负介电各向异性的特定化合物。液晶复合材料可进一步包含具有高上限温度或低下限温度的特定化合物。
• Liquid crystal composition and liquid crystal display device
  申请人：JNC CORPORATION

  公开号：US10442992B2

  公开（公告）日：2019-10-15

  A nematic liquid crystal composition has negative dielectric anisotropy and contains at least one polar compound selected from the group of compounds represented by formula (1) as a first additive, and the liquid crystal display device includes the composition. In formula (1), R1 is hydrogen, halogen, alkyl having 1 to 12 carbons or the like; R2 is a group represented by —OH, —OR0, —NH2, —NHR0 or —N(R0)2, in which R0 is alkyl having 1 to 5 carbons; ring A and ring B are independently 1,4-cyclohexylene, 1,4-phenylene or the like; Z1 is a single bond or the like; Sp1 and Sp2 are independently a single bond, alkylene having 1 to 7 carbons or the like; and a is 0 to 4.

  一种向列液晶组合物具有负介电各向异性，含有至少一种选自式（1）表示的化合物组的极性化合物作为第一添加剂，液晶显示装置包括该组合物。在式 (1) 中，R1 是氢、卤素、具有 1 至 12 个碳原子的烷基或类似物；R2 是由 -OH、-OR0、-NH2、-NHR0 或 -N(R0)2 所代表的基团，其中 R0 是具有 1 至 5 个碳原子的烷基；环 A 和环 B 独立地为 1,4-环己烯、1,4-亚苯基或类似物；Z1 为单键或类似物；Sp1 和 Sp2 独立地为单键、具有 1 至 7 个碳原子的亚烷基或类似物；以及 a 为 0 至 4。
• Method for manufacturing liquid crystal display device and liquid crystal display device
  申请人：JNC CORPORATION

  公开号：US10428275B2

  公开（公告）日：2019-10-01

  A method for manufacturing a liquid crystal display device using a liquid crystal composition containing a polar compound having a polymerizable group. Upon manufacturing the liquid crystal display device including a pair of substrates that have no alignment film and arranged to face each other, and including a liquid crystal composition containing a liquid crystal compound and a polymerizable compound as a liquid crystal layer formed between the substrates formed of an electrode group formed on either one or both of surfaces faced by each of the pair of substrates, in which at least one of the polymerizable compounds is a compound having a polar anchor group, wherein the polymerizable compound is allowed to react under conditions of 10 or more in an accumulated light quantity ratio (313 nm/254 nm) at 254 nanometers and 313 nanometers to form an alignment control layer.

  一种使用含有具有可聚合基团的极性化合物的液晶组合物制造液晶显示装置的方法。在制造液晶显示装置时，该装置包括一对没有对准膜并面对面排列的基板，并包括含有液晶化合物和可聚合化合物的液晶组合物，该液晶组合物作为液晶层形成于这对基板之间，该液晶层由在这对基板各自面对的一个或两个表面上形成的电极组构成、其中至少一种可聚合化合物是具有极性锚基的化合物，在 254 纳米和 313 纳米的累积光量比（313 纳米/254 纳米）为 10 或以上的条件下，使可聚合化合物发生反应，以形成排列控制层。
• Liquid crystal composition, liquid crystal element, and use of liquid crystal composition in liquid crystal element
  申请人：JNC CORPORATION

  公开号：US10982146B2

  公开（公告）日：2021-04-20

  A liquid crystal composition including liquid crystalline compounds, polymerizable compounds, and dichroic dyes in which the polymerizable compound includes at least one compound represented by Formula (1), R11-MES-Sp11-P11  (1) in Formula (1), R11 is an alkyl group having 1 to 15 carbon atoms; MES is a mesogenic group having at least one ring, and in the ring in MES, at least one hydrogen atom is optionally substituted with -Sp11-P11; Sp11 is a single bond or an alkylene group having 1 to 10 carbon atoms, and in this alkylene group, at least one —CH2— is optionally substituted with —O—, —CO—, —COO—, —OCO—, or —OCOO—, and at least one —(CH2)2— is optionally substituted with —CH═CH— or —C≡C—, and in these groups, at least one hydrogen atom is optionally substituted with a polymerizable group; P11 is a polymerizable group or a polar group, or a group having both polymerization and polarity.

  一种液晶组合物，包括液晶化合物、可聚合化合物和二色性染料，其中可聚合化合物包括至少一种由式 (1) 表示的化合物、 R11-MES-Sp11-P11 (1) 在式 (1) 中，R11 是具有 1 至 15 个碳原子的烷基；MES 是具有至少一个环的介原基，在 MES 的环中，至少一个氢原子任选被-Sp11-P11 取代；Sp11 是单键或具有 1 至 10 个碳原子的亚烷基，在该亚烷基中，至少有一个-CH2-被-O-、-CO-、-COO-、-OCO-或-OCOO-任选取代，至少有一个-(CH2)2-被-CH═CH-或-C≡C-任选取代，在这些基团中，至少有一个氢原子被可聚合基团任选取代；P11 是可聚合基团或极性基团，或同时具有聚合性和极性的基团。
• LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：JNC Corporation

  公开号：EP3392324B1

  公开（公告）日：2020-12-09