1-(4-Chlorophenyl)-6-ethoxyhexan-1-one | 61719-26-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(4-Chlorophenyl)-6-ethoxyhexan-1-one
• CAS: 61719-26-4
• 化学式: C₁₄H₁₉ClO₂
• 分子量: 254.75
• InChiKey: JALPGJKSTDFZGS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Use of combinations comprising a corticosteroid and a pyrimidopyrimidine in the treatment of inflammatory diseases
  申请人：Combinatorx, Incorporated

  公开号：EP2070550A1

  公开（公告）日：2009-06-17

  The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.

  本发明的特点是通过向患者单独或与一种或多种附加制剂联合使用四取代嘧啶嘧啶，治疗被诊断患有或有可能患上免疫炎症性疾病的患者。本发明的另一个特点是含有四取代嘧啶嘧啶的组合物与一种或多种附加制剂的组合物。
• EP1680121A4
  申请人：——

  公开号：EP1680121A4

  公开（公告）日：2007-12-26
• METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS
  申请人：CombinatoRx, Incorporated

  公开号：EP1680121A2

  公开（公告）日：2006-07-19
• EP2301628A1
  申请人：——

  公开号：EP2301628A1

  公开（公告）日：2011-03-30
• [EN] METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS<br/>[FR] PROCEDES ET REACTIFS POUR LE TRAITEMENT DE TROUBLES INFLAMMATOIRES
  申请人：COMBINATORX INC

  公开号：WO2005037203A2

  公开（公告）日：2005-04-28

  The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.