脱氧胞苷硫代三磷酸酯 | 64145-29-5

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 中文名称: 脱氧胞苷硫代三磷酸酯
• 英文名称: dCTP(α-S)
• 英文别名: Dctpalphas；[[(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate
• CAS: 64145-29-5
• 化学式: C₉H₁₆N₃O₁₂P₃S
• 分子量: 483.226
• InChiKey: CBYOGVVSAABFCZ-JURLQNGUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  263
• 氢给体数：
  6
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  2'-脱氧胞嘧啶核苷 生成 脱氧胞苷硫代三磷酸酯
  参考文献：
  名称：

  Simple synthesis and separation of the diastereomers of α-thio analogs of ribo- and deoxyribo- di- and triphosphates

  摘要：

  DOI：

  10.1016/s0040-4039(00)84859-5

文献信息

• Method for reducing inhibitors of nucleic acid hybridization
  申请人：Becton, Dickinson and Company

  公开号：EP0851032A1

  公开（公告）日：1998-07-01

  The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid from cells of interest and involves contacting the sample with an agent which solubilizes the inhibitory substances and does not effectuate release of nucleic acids from cells in the sample, and then the cells from the agent.

  本发明涉及一种减少样品中抑制核酸杂交物质含量的方法。该方法在目标核酸从相关细胞中释放出来之前进行，包括将样品与一种药剂接触，该药剂可溶解抑制物质，但不会影响核酸从样品中的细胞释放出来，然后再将细胞从药剂中分离出来。
• Amplification and detection of campylobacter jejuni and campylobacter coli
  申请人：Becton, Dickinson and Company

  公开号：EP1045030A2

  公开（公告）日：2000-10-18

  Amplification primers and methods for specific amplification and detection of a Campylobacter jejuni and C. coli target are disclosed. The primer-target binding sequences are useful for amplification and detection of C jejuni and C. coli target in a variety of amplification and detection reactions.

  本发明公开了特异性扩增和检测空肠弯曲杆菌和大肠杆菌目标的扩增引物和方法。引物-靶标结合序列可用于在各种扩增和检测反应中扩增和检测空肠弯曲菌和大肠杆菌靶标。
• Amplification and detection of Yersinia enterocolitica
  申请人：Becton, Dickinson and Company

  公开号：EP1045031A2

  公开（公告）日：2000-10-18

  Amplification primers and methods for specific amplification and detection of a Yersinia enterocolitica target are disclosed. The primer-target binding sequences are useful for amplification and detection of Y. enterocolitica target in a variety of amplification and detection reactions.

  本发明公开了用于特异性扩增和检测小肠结肠耶尔森菌靶标的扩增引物和方法。引物-靶标结合序列可用于在各种扩增和检测反应中扩增和检测小肠结肠炎耶尔森菌靶标。
• Amplification and detection of shiga-like toxin I producing organisms
  申请人：Becton, Dickinson and Company

  公开号：EP1045033A2

  公开（公告）日：2000-10-18

  Amplification primers and methods for specific amplification and detection of a Shiga-like toxin I (SLT-I) target are disclosed. The primer-target binding sequences are useful for amplification and detection of SLT-I target in a variety of amplification and detection reactions.

  本发明公开了用于特异性扩增和检测志贺样毒素 I（SLT-I）靶标的扩增引物和方法。引物-靶标结合序列可用于在各种扩增和检测反应中扩增和检测 SLT-I 靶标。
• Amplification and detection of shiga-like toxin II producing organisms
  申请人：Becton, Dickinson and Company

  公开号：EP1045034A2

  公开（公告）日：2000-10-18

  Amplification primers and methods for specific amplification and detection of a Shiga-like toxin II (SLT-II) target are disclosed. The primer-target binding sequences are useful for amplification and detection of SLT-II target in a variety of amplification and detection reactions.

  本发明公开了用于特异性扩增和检测志贺样毒素 II（SLT-II）靶标的扩增引物和方法。引物-靶标结合序列可用于在各种扩增和检测反应中扩增和检测 SLT-II 靶标。