1-bromo-2,3,4,10,10a-pentaaza-cyclopenta[b]fluoren-9-one | 941568-61-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-bromo-2,3,4,10,10a-pentaaza-cyclopenta[b]fluoren-9-one
• 英文别名: 12-Bromo-10,11,13,14,16-pentazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(16),2,4,6,9,12,14-heptaen-8-one
• CAS: 941568-61-2
• 化学式: C₁₁H₄BrN₅O
• 分子量: 302.09
• InChiKey: MLEIYTSUGWMSTC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  73
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
  申请人：Hybrigenics S.A.

  公开号：EP1798232A1

  公开（公告）日：2007-06-20

  The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use, as inhibitors of cysteine proteases.

  本发明涉及公式（I）的新化合物，它们的制备过程以及作为半胱氨酸蛋白酶抑制剂的治疗用途。
• Novel inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
  申请人：Guedat Philippe

  公开号：US20070135439A1

  公开（公告）日：2007-06-14

  The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.

  本发明涉及式（I）的新化合物，它们的制备方法以及它们的治疗用途。
• INHIBITORS OF CYSTEINE PROTEASES, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS
  申请人：Hybrigenics S.A.

  公开号：EP1963328B1

  公开（公告）日：2013-10-30
• Novel Inhibitors of Cysteine Proteases, the Pharmaceutical Compositions Thereof and their Therapeutic Applications
  申请人：Guedat Philippe

  公开号：US20090181972A1

  公开（公告）日：2009-07-16

  The present invention concerns new compounds of formula (I), their process of preparation and their therapeutic use.
• US7462615B2
  申请人：——

  公开号：US7462615B2

  公开（公告）日：2008-12-09