1-Ethyl-2-methylcyclobutan-1-ol | 823795-50-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Ethyl-2-methylcyclobutan-1-ol
• CAS: 823795-50-2
• 化学式: C₇H₁₄O
• 分子量: 114.19
• InChiKey: DFWYHRDRGPNELK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Processes for the production of tetrahydrofuran, gamma-butyrolactone and/or butanediol from salts of succinic acid
  申请人：BioAmber S.A.S.

  公开号：EP2371798A1

  公开（公告）日：2011-10-05

  A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth; distilling the broth under super atmospheric pressure at a temperature of >100°C to about 300°C to form an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt% water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; recovering the solid portion; hydrogenating the solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product including at least one of THF, GBL or BDO; and recovering the hydrogenated product.

  一种制备氢化产品的过程包括提供含有澄清DAS的发酵液；在超大气压下将发酵液在温度>100°C至约300°C下蒸馏，形成包括水和氨的顶部产物，以及包括SA和至少约20重量％水的液体底物；将底物冷却至足以使底物分离为与几乎纯净的SA接触的液体部分和固体部分；将固体部分与液体部分分离；回收固体部分；在至少一种氢化催化剂的存在下氢化固体部分，以产生包括THF、GBL或BDO中至少一种的氢化产品；并回收氢化产品。
• PROCESSES FOR THE PRODUCTION OF HYDROGENATED PRODUCTS
  申请人：Fruchey Olan S.

  公开号：US20110245514A1

  公开（公告）日：2011-10-06

  A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth; distilling the broth under super atmospheric pressure at a temperature of >100° C. to about 300° C. to form an overhead that includes water and ammonia, and a liquid bottoms that includes SA, and at least about 20 wt % water; cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a liquid portion in contact with a solid portion that is substantially pure SA; separating the solid portion from the liquid portion; recovering the solid portion; hydrogenating the solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product including at least one of THF, GBL or BDO; and recovering the hydrogenated product.

  制备氢化产品的过程包括提供澄清的含DAS的发酵液；在超大气压下，将发酵液在温度>100°C至约300°C下蒸馏，形成包括水和氨的顶部液体和包括SA和至少约20重量%水的底部液体；将底部冷却至足以使其分离成与实质纯SA接触的液体部分和固体部分；将固体部分与液体部分分离；回收固体部分；在至少一种氢化催化剂的存在下氢化固体部分，以生产包括THF、GBL或BDO中至少一种的氢化产品；并回收氢化产品。
• PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVE
  申请人：Meiji Seika Pharma Co., Ltd.

  公开号：EP2426124A1

  公开（公告）日：2012-03-07

  Disclosed is a process for efficiently producing pyripyropene derivatives having acyloxy at the 1-position and 11-position and hydroxyl at the 7-position. The process comprises selectively acylating hydroxyl at the 1-position and 11-position of a compound represented by formula B1 through one to three steps with an acylating agent in the presence or absence of a base.

  本发明公开了一种高效生产 1 位和 11 位为酰氧基、7 位为羟基的吡丙烯衍生物的工艺。该工艺包括在碱存在或不存在的情况下，用酰化剂通过一至三个步骤，选择性地将式 B1 所代表化合物的 1 位和 11 位上的羟基酰化。