| 207989-27-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 207989-27-3
• 化学式: C₃₇H₃₈N₄O₉
• 分子量: 682.73
• InChiKey: YWSFQPSDKNGGCP-WJOKGBTCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.27
• 重原子数：
  50.0
• 可旋转键数：
  10.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  173.88
• 氢给体数：
  4.0
• 氢受体数：
  10.0

反应信息

• 作为反应物：
  描述：

  对甲苯磺酸 、 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以94%的产率得到(R)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid 4-guanidino-phenyl ester; compound with toluene-4-sulfonic acid
  参考文献：
  名称：

  Methyltrypsin-Catalyzed Peptide Coupling: Comparison of Alkyl Ester and Guanidinophenyl Ester Derivatives as Acyl Donor Component

  摘要：

  Methyltrypsin-catalyzed peptide synthesis has been studied by using conventional alkyl ester and p-guanidinophenyl ester derivatives of alpha-amino acid as the acyl donor component. They were found to be coupled with alpha-amino acid derivatives (acyl acceptor component) to produce dipeptide. The behavior of methyltrypsin toward both the substrates has been studied. (C) 1997 Academic Press.

  DOI：

  10.1006/bioo.1997.1076
• 作为产物：
  描述：

  N-Boc-D-tyrosine p-nitrophenyl ester 在 palladium on activated charcoal 氢气 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Methyltrypsin-Catalyzed Peptide Coupling: Comparison of Alkyl Ester and Guanidinophenyl Ester Derivatives as Acyl Donor Component

  摘要：

  Methyltrypsin-catalyzed peptide synthesis has been studied by using conventional alkyl ester and p-guanidinophenyl ester derivatives of alpha-amino acid as the acyl donor component. They were found to be coupled with alpha-amino acid derivatives (acyl acceptor component) to produce dipeptide. The behavior of methyltrypsin toward both the substrates has been studied. (C) 1997 Academic Press.

  DOI：

  10.1006/bioo.1997.1076