1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-(R)-benzylidene-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-O⁵-[O²,O³;O⁴,O⁶-(Ξ,R)-dibenzylidene-α-D-mannopyranosyl-(1->4)-2,6-bis-benzyloxycarbonylamino-O³-methanesulfonyl-β-L-2,6-dideoxy-idopyranosyl-(1->3)-O²,O⁵-bis-methanesulfonyl-β-D-ribofuranosyl]-2-deoxy-streptamine | 56983-04-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-(R)-benzylidene-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-O⁵-[O²,O³;O⁴,O⁶-(Ξ,R)-dibenzylidene-α-D-mannopyranosyl-(1->4)-2,6-bis-benzyloxycarbonylamino-O³-methanesulfonyl-β-L-2,6-dideoxy-idopyranosyl-(1->3)-O²,O⁵-bis-methanesulfonyl-β-D-ribofuranosyl]-2-deoxy-streptamine
• CAS: 56983-04-1
• 化学式: C₈₆H₉₅N₅O₃₃S₃
• 分子量: 1822.91
• InChiKey: AUQUCODPJAHWGC-GMMAJGHUSA-N

反应信息

• 作为产物：
  描述：

  1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-(R)-benzylidene-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-O⁵-[O²,O³;O⁴,O⁶-(Ξ,R)-dibenzylidene-α-D-mannopyranosyl-(1->4)-2,6-bis-benzyloxycarbonylamino-β-L-2,6-dideoxy-idopyranosyl-(1->3)-β-D-ribofuranosyl]-2-deoxy-streptamine 、 甲基磺酰氯 在 吡啶 作用下， 生成 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-(R)-benzylidene-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-O⁵-[O²,O³;O⁴,O⁶-(Ξ,R)-dibenzylidene-α-D-mannopyranosyl-(1->4)-2,6-bis-benzyloxycarbonylamino-O³-methanesulfonyl-β-L-2,6-dideoxy-idopyranosyl-(1->3)-O²,O⁵-bis-methanesulfonyl-β-D-ribofuranosyl]-2-deoxy-streptamine
  参考文献：
  名称：

  Synthesis of 1-N-[(S)-4-Amino-2-hydroxybutyryl]lividomycin A

  摘要：

  The title compound (7), which is active against resistant bacteria producing phosphotransferase I, was synthesized from lividomycin A through a cyclic carbamate derivative (3). Selective hydrolysis of the carbamate ring followed by acylation of the free C-1-amino group with (S)-2-hydroxy-4-aminobutyric acid by the active ester method led to 7.

  DOI：

  10.1246/bcsj.48.2124