Trimethylsilyl-3-benzyl-O²,,O⁴,O⁶-tris-trimethylsilyl-α-D-glucopyranosid> | 18967-92-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Trimethylsilyl-3-benzyl-O²,,O⁴,O⁶-tris-trimethylsilyl-α-D-glucopyranosid>
• CAS: 18967-92-5
• 化学式: C₂₅H₅₀O₆Si₄
• 分子量: 559.01
• InChiKey: VBQSTZPZSZMLAM-NHTNDUFYSA-N

反应信息

• 作为反应物：
  描述：

  Trimethylsilyl-3-benzyl-O²,,O⁴,O⁶-tris-trimethylsilyl-α-D-glucopyranosid> 在 ammonium acetate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 9.0h， 以90%的产率得到
  参考文献：
  名称：

  Regioselective 6-detrimethylsilylation of per-O-TMS-protected carbohydrates in the presence of ammonium acetate

  摘要：

  A convenient methodology has been developed for the regioselective removal of primary trimethylsilyl group (TMS) of various per-O-TMS-protected carbohydrates by inexpensive ammonium acetate. After acetylation and trichloroacetimidation of 6-hydroxyl sugar 1b, other TMS groups of 1d and 1c were inert to ammonium acetate in the same conditions, and this approach was also successfully applied in TMS-protected sphingosine. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.039