trans-Tetrahydroisocohumulon | 1083063-75-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: trans-Tetrahydroisocohumulon
• 英文别名: trans-Tetrahydroisocohumulone；(4R,5R)-3,4-dihydroxy-5-(3-methylbutyl)-4-(4-methylpentanoyl)-2-(2-methylpropanoyl)cyclopent-2-en-1-one
• CAS: 1083063-75-5
• 化学式: C₂₀H₃₂O₅
• 分子量: 352.471
• InChiKey: CRWKJKKCCCAXET-XOBRGWDASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  91.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Methods and Compositions for Promoting Bone and Joint Health
  申请人：Tripp Matthew L.

  公开号：US20080242690A1

  公开（公告）日：2008-10-02

  Methods and compositions that can be used to promote bone and joint health through amelioration, stabilization and repair of damage associated with various pathophysiological conditions are disclosed.
• Methods and Compositions for Heavy Metal Detoxification
  申请人：Tripp Matthew L.

  公开号：US20090155382A1

  公开（公告）日：2009-06-18

  Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzymes, such as glutathione S-transferases (GSTs), and NADPH quinone reductase (NQO1) activity.
• METHODS AND COMPOSITIONS FOR PROMOTING BONE AND JOINT HEALTH
  申请人：Tripp Matthew L.

  公开号：US20100069422A1

  公开（公告）日：2010-03-18

  Methods and compositions that can be used to promote bone and joint health through amelioration, stabilization and repair of damage associated with various pathophysiological conditions are disclosed.
• SUBSTITUTED 1,3-CYCLOPENTADIONE MULTI-TARGET PROTEIN KINASE MODULATORS OF CANCER, ANGIOGENESIS AND THE INFLAMMATORY PATHWAYS ASSOCIATED THEREWITH
  申请人：Tripp Matthew L.

  公开号：US20100137449A1

  公开（公告）日：2010-06-03

  Compounds and methods for multi-targeted protein kinase modulation for angiogenesis, cancer treatment or the inflammatory pathways associated with those conditions are disclosed. The compounds and methods disclosed are based on substituted 1,3-cyclopentadione compounds.
• SUBSTITUTED 1, 3-CYCLOPENTADIONE ATTENUATED ENDOTHELIAL INFLAMMATION AND ENDOTHELIAL-MONOCYTE INTERACTIONS
  申请人：Konda Veera

  公开号：US20100222262A1

  公开（公告）日：2010-09-02

  Compositions and methods for reducing cardiovascular risk utilizing substituted 1,3-cyclopentadione compounds are described.