2-(3-Ethoxypropoxy)ethanamine | 883539-34-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(3-Ethoxypropoxy)ethanamine
• CAS: 883539-34-2
• 化学式: C₇H₁₇NO₂
• 分子量: 147.22
• InChiKey: HATSINZMFRCCNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  10
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Fluorescent naphthalene -1,4,5,8-tetracarboxylic bisimides with an electron-donating substituent on the nucleus
  申请人：——

  公开号：US20030153005A1

  公开（公告）日：2003-08-14

  Naphthalene-1,4,5,8-tetracarboxylic bisimides of the general formula I 1 where the variables are defined as follows: R 1 and R 2 independently of one another are hydrogen, substituted or unsubstituted alkyl or substituted or unsubstituted aryl; X and Y independently of one another are halogen, amino or a radical with the formula —NHR 3 , —OR 3 , where R 3 has the formula —CH 2 R 4 , —CHR 4 R 5 , or —CR 4 R 5 R 6 , where R 4 , R 5 , and R 6 independently of one another are hydrogen, substituted or unsubstituted alkyl, aryl, alkoxy, alkylthio, aryloxy or arylthio, and at least one of the two substituents X and Y is other than halogen, their preparation and use as fluorescent dyes, for coloring high molecular mass organic materials and inorganic materials, as laser dyes, and also for fluorescence marking and as fluorescent labels for biomolecules.
• Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus
  申请人：Tamada Sakuya

  公开号：US20060088786A1

  公开（公告）日：2006-04-27

  A rewritable optical information recording medium including a recording layer composed of an organic dye film is provided, in which recording and erasing information can be performed reversibly by laser light irradiation. A rewritable optical information recording medium including at least one organic dye film which is substantially made of only at least one kind of organic dye compounds as a recording film is provided. The recording and erasure of information are performed by a reversible physical change of the organic dye film substance caused by laser light irradiation. Specifically, data recording is performed by a physical change locally caused by the irradiation of recording laser light, data reproduction is performed by detecting change in intensity of returned light of reproducing laser light having less power than the recording laser light, and data erasure is performed by applying at least once continuous light or pulse light having laser power more than the reproducing laser light and less than the recording laser light. The physical change is a change in shape.
• MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS
  申请人：Nektar Therapeutics

  公开号：US20210128737A1

  公开（公告）日：2021-05-06

  Provided are multi-arm polymer conjugates of Toll-Like Receptor (“TLR”) agonists such as TLR 7/8 agonists, as well as related compositions, and methods of making and using such conjugates. Exemplary conjugates are encompassed by Formula I: (I) or a pharmaceutically acceptable salt form thereof, where R, taken together with each Q, is a residue of a polyol, polythiol, or polyamine bearing from 3 to about 50 hydroxyl, thiol, or amino groups; each Q is a linker selected from oxygen, sulfur and —NH; each POLY is independently a water-soluble, non-peptidic polymer; each Xr is independently a linkage-containing spacer moiety; q is a positive integer from 3 to about 50; and each TLR 7/8 AG is a Toll-like receptor 7/8 agonist. Also provided is a method of administering to a patient having cancer (a) an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; and (b) a Toll-like receptor agonist such as a conjugate as described above, as well as related compositions, kits and methods. R Q-POLY-Xr-TLR 7/8 AG) q (I)
• US7605263B2
  申请人：——

  公开号：US7605263B2

  公开（公告）日：2009-10-20