tert-butyl((8-(2,2-dimethyl-1,3-dioxolan-4-yl)octyl)oxy)dimethylsilane | 1318779-95-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: tert-butyl((8-(2,2-dimethyl-1,3-dioxolan-4-yl)octyl)oxy)dimethylsilane
• CAS: 1318779-95-1
• 化学式: C₁₉H₄₀O₃Si
• 分子量: 344.61
• InChiKey: QABQZOJZGMIIHZ-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  tert-butyl((8-(2,2-dimethyl-1,3-dioxolan-4-yl)octyl)oxy)dimethylsilane 在 phosphotungstic acid 、 水 作用下， 以 乙腈 为溶剂， 反应 1.0h， 以82%的产率得到10-((tert-butyldimethylsilyl)oxy)decane-1,2-diol
  参考文献：
  名称：

  Useful methods for the synthesis of isopropylidenes and their chemoselective cleavage

  摘要：

  A catalytic amount of phosphotungstic acid (PTA) has been found to be a very effective catalyst for isopropylidenation of 1,2-diols and their deprotection at room temperature. The ease of handling, cost and activity of the catalyst, good to excellent yields and chemoselectivity for deprotection are some of the highlights of the reported method. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.050