2,11,20-tris(phenylmethyl)-4,13,22,28,29,30-hexaoxatetracyclo[23.2.1.1(7,10).1(16,19)]triaconta-1(27),7,9,16,18,25-hexaene-3,12,21-trione | 1185763-09-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 2,11,20-tris(phenylmethyl)-4,13,22,28,29,30-hexaoxatetracyclo[23.2.1.1(7,10).1(16,19)]triaconta-1(27),7,9,16,18,25-hexaene-3,12,21-trione
• CAS: 1185763-09-0
• 化学式: C₄₅H₄₂O₉
• 分子量: 726.823
• InChiKey: GFROOFXQPKTWEY-UHFFFAOYSA-N

物化性质

• 沸点：
  938.9±65.0 °C(predicted)
• 密度：
  1.195±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  2-(5-(2-hydroxyethyl)furan-2-yl)-3-phenylpropanoic acid 在 4-二甲氨基吡啶 、 potassium carbonate 、 2,6-二氯苯甲酰氯 作用下， 以 二氯甲烷 为溶剂， 以3.5%的产率得到2,11-bis(phenylmethyl)-4,13,19,20-tetraoxatricyclo[14.2.1.1(7,10)]icosa-1(18),7,9,16-tetraene-3,12-dione
  参考文献：
  名称：

  Macrocyclisation of 2-(5-(2-hydroxyethyl)furan-2-yl)acetic acid model compounds of nonactic acid

  摘要：

  The macrocyclisation of hydroxyethylfuranyl acetic acid and of dehydrogenated model compounds of nonactic acid was investigated to develop a facile synthesis of nonactin analogues. By applying the Yamagushi macrocyclisation to our omega-hydroxyacids, we were able to isolate a mixture of di-, tri-, tetra- and pentameric macrocycles.

  DOI：

  10.1007/s00706-008-0031-4