申请人:BAYER AG
公开号:EP0551662A1
公开(公告)日:1993-07-21
Benzofuranyl- and thiophenylmethylthio-alkanecarboxylic acid derivatives are prepared by brominating appropriate methyl compounds and reacting the methyl bromides thus obtained with mercapto-alkanecarboxylic acid derivatives. The new substances are suitable as NADPH oxidase inhibitors for use in medicaments, in particular for the treatment of acute and chronic inflammatory processes.
苯并呋喃基和
硫代苯基甲
硫基烷基
羧酸衍
生物是通过对适当的甲基化合物进行
溴化并将得到的甲基
溴化物与巯基-烷基
羧酸衍
生物反应制备而成。这些新物质适用于作为
NADPH氧化酶
抑制剂用于药物,特别是用于治疗急性和慢性炎症过程。