N-methyl-4-(pyridin-2-yloxy)aniline | 1184735-72-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-methyl-4-(pyridin-2-yloxy)aniline
• 英文别名: N-methyl-4-pyridin-2-yloxyaniline
• CAS: 1184735-72-5
• 化学式: C₁₂H₁₂N₂O
• mdl: MFCD12779335
• 分子量: 200.24
• InChiKey: AUHHWJBGADUWTH-UHFFFAOYSA-N

物化性质

• 沸点：
  341.3±22.0 °C(Predicted)
• 密度：
  1.159±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.083
• 拓扑面积：
  34.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF
  申请人：Beijing Scitech-MQ Pharmaceuticals Limited

  公开号：EP3760633B1

  公开（公告）日：2021-12-15
• OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF
  申请人：BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED

  公开号：US20210040114A1

  公开（公告）日：2021-02-11

  Provided are an oxazino-quinazoline and oxazino-quinoline type compound, a preparation method, and uses thereof. More particularly provided is a compound shown in formula (I), an isomer, a hydrate, a solvate, a pharmaceutically acceptable salt, a prodrug thereof, a preparation method, and uses thereof in preparing a drug acting as a kinase inhibitor.