3,5,5-Trimethylheptan-2-one | 89319-94-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,5,5-Trimethylheptan-2-one
• CAS: 89319-94-8
• 化学式: C₁₀H₂₀O
• 分子量: 156.26
• InChiKey: CYFVNVPQFJBHEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS
  申请人：Yu Chongxi

  公开号：US20110269689A1

  公开（公告）日：2011-11-03

  High penetration compositions (HPC) of a parent compound, which are capable of crossing biological barriers with high penetration efficiency. The HPCs are capable of being converted to parent drugs or parent drug-related compounds such as metabolites after crossing one or more biological barriers and thus can render treatments for the conditions that the parent drugs or parent drug-related compounds can. Additionally, the HPCs are capable of reaching areas that their parent drugs or parent drug-related compounds may not be able to access or to render a sufficient concentration at the target areas HPCs of NSAIA, for example, have demonstrated indications such as treating hair loss. A HPC can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.