1-(1,1-Dimethyl-prop-2-ynyloxy)-pentane | 55361-22-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(1,1-Dimethyl-prop-2-ynyloxy)-pentane
• 英文别名: 1-(2-Methylbut-3-yn-2-yloxy)pentane
• CAS: 55361-22-3
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: GZWWHUBMEYRGCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• PYRAZOLOPYRIMIDINE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
  申请人：VIIV HEALTHCARE (NO.5) LIMITED

  公开号：EP3107918A1

  公开（公告）日：2016-12-28
• [EN] PYRAZOLOPYRIMIDINE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION<br/>[FR] MACROCYCLES DE PYRAZOLOPYRIMIDINE EN TANT QU'INHIBITEURS DE LA RÉPLICATION DU VIRUS DE L'IMMUNODÉFICIENCE HUMAINE
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2015126737A1

  公开（公告）日：2015-08-27

  The disclosure generally relates to compounds of formula (I), including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for making and using these compounds in the treatment of HIV infection.