3-ethyl-5-vinyl-dihydro-furan-2-one | 27927-40-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 3-ethyl-5-vinyl-dihydro-furan-2-one
• 英文别名: 3-Aethyl-5-vinyl-dihydro-furan-2-on；5-Ethenyl-3-ethyloxolan-2-one
• CAS: 27927-40-8
• 化学式: C₈H₁₂O₂
• 分子量: 140.182
• InChiKey: USKSUYDLXSPNGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-ethyl-2-oxo-5-vinyl-tetrahydro-furan-3-carboxylic acid ethyl ester 在 氢氧化钾 作用下， 生成 3-ethyl-5-vinyl-dihydro-furan-2-one
  参考文献：
  名称：

  The Preparation of 5-Alkyl-5-(β-phenyl- and β-Vinyl-β-hydroxyethyl)-barbituric Acids Via the Corresponding α-Carbethoxy-γ-butyrolactones

  摘要：

  DOI：

  10.1021/ja01159a075

文献信息

• Alpha-Amino-N-Substituted Amides, Pharmaceutical Composition Containing Them and Uses Thereof
  申请人：Nan Fajun

  公开号：US20110021624A1

  公开（公告）日：2011-01-27

  Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.
• US8470763B2
  申请人：——

  公开号：US8470763B2

  公开（公告）日：2013-06-25
• The Preparation of 5-Alkyl-5-(β-phenyl- and β-Vinyl-β-hydroxyethyl)-barbituric Acids Via the Corresponding α-Carbethoxy-γ-butyrolactones
  作者：Gerrit Van Zyl、Eugene E. van Tamelen

  DOI：10.1021/ja01159a075

  日期：1950.3