2-[4-(Dimethylamino)phenyl]-3-methylchromen-4-one | 1233712-94-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-[4-(Dimethylamino)phenyl]-3-methylchromen-4-one
• CAS: 1233712-94-1
• 化学式: C₁₈H₁₇NO₂
• 分子量: 279.338
• InChiKey: QQZVZFHPNLTXPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-Dimethylamino-α-methyl-2'-hydroxy-chalkon 在 碘 作用下， 以 二甲基亚砜 为溶剂， 以72%的产率得到2-[4-(Dimethylamino)phenyl]-3-methylchromen-4-one
  参考文献：
  名称：

  Jayashree; Alam, Afroze; Kumar, D. Vijay, Indian Journal of Heterocyclic Chemistry, 2010, vol. 19, # 3, p. 237 - 240

  摘要：

  DOI：

文献信息

• Jayashree; Alam, Afroze; Kumar, D. Vijay, Indian Journal of Heterocyclic Chemistry, 2010, vol. 19, # 3, p. 237 - 240
  作者：Jayashree、Alam, Afroze、Kumar, D. Vijay、Nayak, Yogendra

  DOI：——

  日期：——
• SUPERCRITICAL NOBLE GASES AND COLORING METHODS
  申请人：Carlson William B.

  公开号：US20120030884A1

  公开（公告）日：2012-02-09

  A coloring system can include a noble gas, colorant, and one or more vessels configured to convert the noble gas into a supercritical fluid, and/or receive and color an article of manufacture with the noble gas in the supercritical fluid state. A coloring process can include converting a noble gas into a supercritical fluid state; dissolving, suspending, or absorbing a colorant into the supercritical noble gas, and coloring an article of manufacture with the noble gas in the supercritical fluid state. A coloring composition can include a noble gas in a supercritical fluid state, and a colorant located in the supercritical noble gas.
• Synthesis of 3-methylflavones and their antioxidant and antibacterial activities
  作者：B. S. Jayashree、Afroze Alam、Yogendra Nayak、D. Vijay Kumar

  DOI：10.1007/s00044-011-9725-y

  日期：2012.8

  An attempt was made to synthesise newer 3-methylflavones with various substitution on the ring A and B of 2-phenylchromen-4-one. They were evaluated for antioxidant activity and antibacterial activity against the Gram-positive and Gram-negative bacteria. Five test compounds exhibited DPPH radical scavenging activity with IC50 below 100 mu g/ml, and the same test compounds exhibited 50-100% growth inhibition in Gram-positive bacteria against standard Amoxicillin.