N-[(1R,2R)-2-(3,4-dimethoxyphenyl)cyclohexyl]-3-acetobenzamide | 284676-23-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[(1R,2R)-2-(3,4-dimethoxyphenyl)cyclohexyl]-3-acetobenzamide
• 英文别名: 3-acetyl-N-[(1R,2R)-2-(3,4-dimethoxyphenyl)cyclohexyl]benzamide
• CAS: 284676-23-9
• 化学式: C₂₃H₂₇NO₄
• 分子量: 381.472
• InChiKey: UFLSQPMWZFWAST-WOJBJXKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  64.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] NOVEL 6-PHENYLPHENANTRIDINES<br/>[FR] NOUVELLES 6-PHENYLPHENANTRIDINES
  申请人：ALTANA PHARMA AG

  公开号：WO2005012252A1

  公开（公告）日：2005-02-10

  Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51, R6, R7 and R8 have the meanings indicated in the description, are novel effective PDE4 inhibitors.

  式(I)的化合物，其中R1、R2、R3、R31、R4、R5、R51、R6、R7和R8具有描述中所示的含义，是新颖有效的PDE4抑制剂。
• [EN] NOVEL 6-PHENYLPHENANTHRIDINES<br/>[FR] NOUVELLES 6-PHENYLPHENANTHRIDINES
  申请人：ALTANA PHARMA AG

  公开号：WO2005012253A1

  公开（公告）日：2005-02-10

  Compounds of a certain formula (I), in which R1, R2, R3, R31, R4, R5, R51, R6, R7 and R8 have the meanings indicated in the description, are novel effective PDE4 inhibitors.

  具有以下含义的化合物(I)，其中R1、R2、R3、R31、R4、R5、R51、R6、R7和R8的含义如说明书所示，是新型有效的PDE4抑制剂。
• Novel 6-phenlyphenanthridines
  申请人：Schmidt Beate

  公开号：US20060189641A1

  公开（公告）日：2006-08-24

  Compounds of a certain formula (I) in which R1, R2, R3, R31, R4, R5, R51, R6, R7 and R8 have the meanings indicated in the description, are novel effective PDE4 inhibitors.

  具有特定公式（I）的化合物，在该公式中R1，R2，R3，R31，R4，R5，R51，R6，R7和R8具有描述中指示的含义，是新颖有效的PDE4抑制剂。
• Novel 6-phenylphenantridines
  申请人：Schmidt Beate

  公开号：US20060189645A1

  公开（公告）日：2006-08-24

  Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51, R6, R7 and R8 have the meanings indicated in the description, are novel effective PDE4 inhibitors.

  式(I)的化合物，其中R1、R2、R3、R31、R4、R5、R51、R6、R7和R8具有说明中所示的含义，是新颖有效的PDE4抑制剂。
• 6-Phenylphenanthridines with PDE-IV inhibiting activity
  申请人：ALTANA Pharma AG

  公开号：EP1650193A2

  公开（公告）日：2006-04-26

  Compounds of the formula I, in which R1, R2, R3, R31, R4, R5, R51, R6, R13 and R20 have the meanings indicated in the description, are novel active bronchial therapeutics.

  式 I 的化合物、 其中 R1、R2、R3、R31、R4、R5、R51、R6、R13 和 R20 具有描述中的含义，是新型活性支气管治疗剂。