2-methyl-2-propenyl-4-amyloxymethylbutanolide | 945738-26-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 2-methyl-2-propenyl-4-amyloxymethylbutanolide
• CAS: 945738-26-1
• 化学式: C₁₄H₂₄O₃
• 分子量: 240.343
• InChiKey: NGQCWJZEYSERHI-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  2-methyl-2-propenyl-4-amyloxymethylbutanolide 在 甲酸 、 双氧水 作用下， 反应 20.0h， 以74%的产率得到4-amyloxymethyl-2-(2-methyl-2,3-dihydroxy)propylbutanolide
  参考文献：
  名称：

  Synthesis and some transformations of 2-alkenyl-4-alkoxymethylbutanolides

  摘要：

  The alkylation of 4-alkoxymethyl-2-ethoxycarbonylbutanolides led to the formation of 2-alkenyl-4-alkoxymethyl-2-ethoxycarbonylbutanolides which at alkaline hydrolysis provided new 2-alkenyl-4-alkoxymethylbutanolides. By oxidation of the latter with a mixture of hydrogen peroxide and formic acid 4-alkoxymethyl-2-(2-R-2,3-dihydroxy)propylbutanolides were obtained. The diololactones were shown to suffer under the conditions of the pinacol-pinacolone rearrangement a conversion into previously unknown formyl- and epoxylactones.

  DOI：

  10.1134/s1070428006080136
• 作为产物：
  描述：

  2-methyl-2-propenyl-4-amyloxymethyl-2-ethoxycarbonylbutanolide 在 sodium hydroxide 、 十八烷基二甲基苄基氯化铵 作用下， 以 水 为溶剂， 反应 3.0h， 以90%的产率得到2-methyl-2-propenyl-4-amyloxymethylbutanolide
  参考文献：
  名称：

  Synthesis and some transformations of 2-alkenyl-4-alkoxymethylbutanolides

  摘要：

  The alkylation of 4-alkoxymethyl-2-ethoxycarbonylbutanolides led to the formation of 2-alkenyl-4-alkoxymethyl-2-ethoxycarbonylbutanolides which at alkaline hydrolysis provided new 2-alkenyl-4-alkoxymethylbutanolides. By oxidation of the latter with a mixture of hydrogen peroxide and formic acid 4-alkoxymethyl-2-(2-R-2,3-dihydroxy)propylbutanolides were obtained. The diololactones were shown to suffer under the conditions of the pinacol-pinacolone rearrangement a conversion into previously unknown formyl- and epoxylactones.

  DOI：

  10.1134/s1070428006080136