2,2,4-Tris(hydroxymethyl)-1,3-dioxolan-4-ol | 675841-66-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2,4-Tris(hydroxymethyl)-1,3-dioxolan-4-ol
• CAS: 675841-66-4
• 化学式: C₆H₁₂O₆
• 分子量: 180.16
• InChiKey: UYHAIJBBDSCNPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• USE OF COMPOSITIONS COMPRISING DIHYDROXYACETONE FOR THE PROTECTION OF SKIN OR HAIR AGAINST INFRARED IRRADIATION
  申请人：Merck Patent GmbH

  公开号：EP3791854A1

  公开（公告）日：2021-03-17

  The present invention relates to the non-therapeutical, cosmetic use of dihydroxyacetone in a cosmetic composition to be applied on skin, scalp, or hair for the protection of skin, scalp, or hair against infrared irradiation as well as the use of a cosmetic composition comprising dihydroxyacetone as an agent for controlling tropoelastin expression in living cells of the epidermis and papillary dermis or as an agent for controlling the degradation of extracellular matrix components in living cells of the epidermis and papillary dermis. It further relates to dihydroxyacetone as an active ingredient to protect skin, scalp, or hair against damages after infrared irradiation by reacting with the skin, scalp, or hair or by penetrating the skin, scalp, or hair.

  本发明涉及二羟基丙酮在化妆品组合物中的非治疗性化妆品用途，该化妆品组合物可用于皮肤、头皮或头发，以保护皮肤、头皮或头发免受红外线照射、本发明涉及二羟基丙酮在化妆品组合物中的非治疗性化妆品用途，该组合物可用于皮肤、头皮或头发，以保护皮肤、头皮或头发免受红外线照射，还涉及含有二羟基丙酮的化妆品组合物在表皮和真皮乳头活细胞中作为控制特罗波弹性蛋白表达的制剂或在表皮和真皮乳头活细胞中作为控制细胞外基质成分降解的制剂的用途。它还涉及二羟基丙酮作为一种活性成分，通过与皮肤、头皮或头发发生反应或穿透皮肤、头皮或头发，保护皮肤、头皮或头发免受红外线照射后的损害。
• Self Tanning Composition
  申请人：Ehlis Thomas

  公开号：US20090196894A1

  公开（公告）日：2009-08-06

  Disclosed is a method for the colouration of skin or a keratinic fibre, characterized in that the skin or keratinic fibre is contacted with a formulation containing a dispersion of solid particles of a tanning substance selected from a compound of the formula (I) wherein i is 0 or 1 and each of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 independently of each other is selected from group consisting of hydrogen, OH, C 1 -C 6 alkyl, C 1 -C 6 hydroxyalkyl and C 2 -C 6 al-kenyl; in an organic liquid of low polarity or non-polar organic liquid.
• Use of compositions comprising dihydroxyacetone for the protection of skin or hair against infrared irradiation
  申请人：Merck Patent GmbH

  公开号：US20210077370A1

  公开（公告）日：2021-03-18

  The non-therapeutical, cosmetic use of dihydroxyacetone in a cosmetic composition to be applied on skin, scalp, or hair for the protection of skin, scalp, or hair against infrared irradiation as well as the use of a cosmetic composition containing dihydroxyacetone as an agent for controlling tropoelastin expression in living cells of the epidermis and papillary dermis or as an agent for controlling the degradation of extracellular matrix components in living cells of the epidermis and papillary dermis, and dihydroxyacetone as an active ingredient to protect skin, scalp, or hair against damages after infrared irradiation by reacting with the skin, scalp, or hair or by penetrating the skin, scalp, or hair.
• [EN] SELF TANNING COMPOSITION<br/>[FR] COMPOSITION AUTOBRONZANTE
  申请人：CIBA SC HOLDING AG

  公开号：WO2007137958A2

  公开（公告）日：2007-12-06

  [EN] Disclosed is a method for the colouration of skin or a keratinic fibre, characterized in that the skin or keratinic fibre is contacted with a formulation containing a dispersion of solid particles of a tanning substance selected from a compound of the formula (I) wherein i is 0 or 1 and each of R₁, R₂, R₃, R₄, R₅, R₆, R₇, R₈ independently of each other is selected from group consisting of hydrogen, OH, C₁-C₆alkyl, C₁-C₆hydroxyalkyl and C₂-C₆al- kenyl; in an organic liquid of low polarity or non-polar organic liquid.
  [FR] L'invention porte sur un procédé permettant de colorer la peau ou une fibre kératinique, caractérisé en ce que la peau ou la fibre kératinique est mise en contact avec une formulation contenant une dispersion de particules solides d'une substance bronzante choisie à partir d'un composé de la formule (I) dans laquelle i est 0 ou 1 et R₁, R₂, R₃, R₄, R₅, R₆, R₇, R₈ sont, chacun indépendamment des autres, choisis dans le groupe composé de l'hydrogène, OH, C₁-C₆alkyle, C₁-C₆hydroxyalkyle et C₂-C₆alcényle; dans un liquide organique faiblement polaire ou dans liquide organique non polaire.