5,5-Diethyl-2,2-dimethyl-1,3-dioxane | 876-52-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,5-Diethyl-2,2-dimethyl-1,3-dioxane
• CAS: 876-52-8
• 化学式: C₁₀H₂₀O₂
• 分子量: 172.26
• InChiKey: XOWOPWRJQUHRDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• POLYFUNCTIONAL POLYOXYALKYLENE COMPOUND, AND PRODUCING METHOD AND INTERMEDIATE THEREOF
  申请人：NAKAMOTO Ken-ichiro

  公开号：US20110245509A1

  公开（公告）日：2011-10-06

  A polyfunctional polyoxyalkylene compound represented by the following formula (1): wherein Z represents a hydroxyl group-removed residue of pentaerythritol or dipentaerythritol, R represents a hydrocarbon group having 1 to 24 carbon atoms, OA 1 and OA 2 represent an oxyalkylene group having 2 to 4 carbon atoms, L 1 and L 2 represent an alkylene group which may have an ester bond or the like in the alkylene chain or at the terminal end, and X represents a functional group capable of reacting chemically; R, OA 1 , OA 2 , L 1 , and L 2 are the same or different from one another in one molecule, m and n are an average number of moles of the oxyalkylene group added, m represents 5 to 1,000, and n represents 0 to 1,000; p and q represent 0 or 1; r 1 +r 2 =4 or 6; and r 1 and r 2 are an integer of 2 or more.

  一个由以下公式（1）表示的多功能聚氧烷基化合物：其中Z代表对苯二醇或重聚对苯二醇的去羟基残基，R代表具有1至24个碳原子的碳氢基团，OA1和OA2代表具有2至4个碳原子的氧烷基团，L1和L2代表可能在烷基链中或末端具有酯键等的烷基团，X代表能够发生化学反应的功能基团；R、OA1、OA2、L1和L2在同一分子中相同或不同，m和n是添加的氧烷基团的平均摩尔数，m表示5至1,000，n表示0至1,000；p和q代表0或1；r1+r2=4或6；r1和r2是大于或等于2的整数。
• METHODS FOR TREATING CANCER AND NON-NEOPLASTIC CONDITIONS
  申请人：Almstead Neil

  公开号：US20120202763A1

  公开（公告）日：2012-08-09

  Compounds that selectively inhibit pathological production of human vascular endothelial growth factor (VEGF) and compositions comprising such Compounds are described. Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of reducing VEGF using such Compounds and methods for treating cancer and non-neoplastic conditions involving the administration of such Compounds. Further described are methods of inhibiting viral replication or the production of viral RNA or DNA or viral protein using such Compounds and methods for treating viral infections involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments.

  本文介绍了选择性抑制人类血管内皮生长因子（VEGF）病理性产生的化合物以及包含这些化合物的组合物。本文还介绍了抑制病毒复制或病毒RNA或DNA或病毒蛋白质产生的化合物以及包含这些化合物的组合物。同时，本文还介绍了使用这些化合物减少VEGF的方法以及使用这些化合物治疗癌症和非肿瘤性疾病的方法。本文还介绍了使用这些化合物抑制病毒复制或病毒RNA或DNA或病毒蛋白质产生的方法以及使用这些化合物治疗病毒感染的方法。这些化合物可以作为单一治疗剂或与一个或多个其他治疗剂联合使用，用于治疗需要这些治疗的人类。
• Copolymerisierbare Polyalkylenglykol-Makromonomere, deren Herstellung und Verwendung
  申请人：Clariant Produkte (Deutschland) GmbH

  公开号：EP1584631B1

  公开（公告）日：2008-11-12
• US7563291B2
  申请人：——

  公开号：US7563291B2

  公开（公告）日：2009-07-21
• US8816099B2
  申请人：——

  公开号：US8816099B2

  公开（公告）日：2014-08-26