perfluoro isopropyl-methyl ether | 55757-37-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: perfluoro isopropyl-methyl ether
• 英文别名: 1-(1,1-Difluoro-2-methylpropoxy)-1,1-difluoro-2-methylpropane
• CAS: 55757-37-4
• 化学式: C₈H₁₄F₄O
• 分子量: 202.192
• InChiKey: ZCEKTBREIHERSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  异丁酸 在 sulfur tetrafluoride 作用下， 生成 1,1,1-trifluoro-2-methylpropane 、 perfluoro isopropyl-methyl ether
  参考文献：
  名称：

  Dmowski,W.; Kolinski,R.A., Roczniki Chemii, 1974, vol. 48, p. 1697 - 1706

  摘要：

  DOI：

文献信息

• Thermal preactivation of gaseous precursor filled compositions
  申请人：IMARX PHARMACEUTICAL CORP.

  公开号：EP0901793A1

  公开（公告）日：1999-03-17

  The present invention describes, among other things, the surprising discovery that gaseous precursor filled compositions are profoundly more effective as acoustically active contrast agents when they are thermally preactivated to temperatures at or above the boiling point of the instilled gaseous precursor prior to their in vivo administration to a patient. Further optimization of contrast enhancement is achieved by administering the gaseous precursor filled compositions to a patient as an infusion. Enhanced effectiveness is also achieved for ultrasound mediated targeting and drug delivery.

  本发明描述了，除其他外，令人惊奇的发现，如果在对患者进行体内给药之前，将充满气态前体的组合物进行热预活化，使其温度达到或超过灌注气态前体的沸点，那么这些组合物作为声学活性造影剂的效果就会大大提高。通过向患者输注充满气态前体的组合物，可进一步优化造影剂的增强效果。此外，还能提高超声波介导的靶向和药物输送的效果。
• Compositions comprising trans-1,2-dichloroethylene and an organic compound, and methods of using the same
  申请人：SHELLEF HOLDINGS INC.

  公开号：US10934507B2

  公开（公告）日：2021-03-02

  Disclosed herein are a solvent composition and methods of using the solvent composition. The solvent composition includes at least 80 wt. % of trans-1,2-dichloroetheylene (t-DCE), and 0.1 to 20 wt. % of at least one organic compound. The organic compound may be a hydrocarbon and/or an oxygenated solvent. The solvent composition may be used to clean a surface by contacting the surface with the composition to dissolve a contaminant on the surface. The composition may be used to remove a coating from a surface of a substrate by contacting the surface with the solvent composition to dissolve the coating and removing the composition containing the coating from the surface. The composition may also be used to deposit material on a substrate by dissolving the material in the solvent composition, applying the composition containing the material onto the substrate, and evaporating the composition from the substrate.

  本文公开了一种溶剂组合物和使用该溶剂组合物的方法。溶剂组合物包括至少 80 重量%的反式-1,2-二氯乙烯（t-DCE）和 0.1 至 20 重量%的至少一种有机化合物。有机化合物可以是碳氢化合物和/或含氧溶剂。溶剂组合物可用来清洁表面，方法是将表面与组合物接触以溶解表面上的污染物。该组合物可用于去除基底表面的涂层，方法是将基底表面与溶剂组合物接触，使涂层溶解，然后将含有涂层的组合物从基底表面去除。该组合物还可用于在基底上沉积材料，方法是将材料溶解在溶剂组合物中，将含有材料的组合物涂在基底上，然后将组合物从基底上蒸发掉。
• Compositions containing trans-1,2-dichloroethylene and a hydrofluoroether, and methods of using the same
  申请人：SHELLEF HOLDINGS INC.

  公开号：US11124744B2

  公开（公告）日：2021-09-21

  Disclosed herein are solvent compositions and methods of using the solvent compositions. The solvent composition includes at least trans-1,2-dichloroethylene (t-DCE) and 1,1,2,2-tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether (TFE-TFPE). The solvent composition may also include an oxygenated solvent, such as an alcohol or fluorinated ether. A method of cleaning the surface of an article includes contacting the surface with the solvent composition to dissolve, disperse, or displace a contaminant on the surface, and removing the solvent composition containing the contaminant from the surface.

  本文公开了溶剂组合物和使用溶剂组合物的方法。溶剂组合物至少包括反式-1,2-二氯乙烯（t-DCE）和 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚（TFE-TFPE）。溶剂组合物还可包括含氧溶剂，如酒精或氟化醚。清洁物品表面的方法包括将物品表面与溶剂组合物接触，以溶解、分散或置换表面上的污染物，并从物品表面去除含有污染物的溶剂组合物。
• OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE
  申请人：IMARX PHARMACEUTICAL CORP.

  公开号：EP1039834B1

  公开（公告）日：2005-09-28
• EP1039834A4
  申请人：——

  公开号：EP1039834A4

  公开（公告）日：2001-12-05