(1R,6S)-3-(1-Hydroxy-1-methyl-ethyl)-8a-methyl-5-methylene-decahydro-azulene-1,6-diol | 133692-86-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1R,6S)-3-(1-Hydroxy-1-methyl-ethyl)-8a-methyl-5-methylene-decahydro-azulene-1,6-diol
• CAS: 133692-86-1
• 化学式: C₁₅H₂₆O₃
• 分子量: 254.37
• InChiKey: YDWQUGFNJYNSAG-BCILHVDJSA-N

反应信息

• 作为产物：
  描述：

  (9E)-(2S*,3S*,6R*,7R*)-2,3;6,7-diepoxy-3,7,11,11-tetramethylcycloundec-9-ene 在 sodium acetate buffer 作用下， 以 乙醇 、 水 为溶剂， 反应 2.0h， 生成 (1R,6S)-3-(1-Hydroxy-1-methyl-ethyl)-8a-methyl-5-methylene-decahydro-azulene-1,6-diol 、 (2Z,8E)-(1S,5R)-2,10,10-Trimethyl-6-methylene-cycloundeca-2,8-diene-1,5-diol 、 (4Z,9E)-(1R,2R,6S)-1,5,8,8-Tetramethyl-cycloundeca-4,9-diene-1,2,6-triol 、 (4Z,9E)-(1R,2S,6R)-1,5,8,8-Tetramethyl-cycloundeca-4,9-diene-1,2,6-triol
  参考文献：
  名称：

  Hydrolysis products of humulene diepoxide A

  摘要：

  Humulene diepoxide A, a flavoring compound found in hops, undergoes hydrolysis reactions upon boiling at pH 4. More than ten hydrolysis products were produced, of which five, 1-5 have been isolated and their structures determined. Two of these compounds, 1 and 2, are diastereomeric humuladiene triols, one is an exo-methylene diol 3, another is a saturated tricyclic triol 4, and the last is a bicyclic triol with an exo-methylene group 5. Aroma/flavor profiles of compounds 1 and 2 indicate that 2 would be more desirable than 1 in brewing.

  DOI：

  10.1016/s0040-4020(01)80933-9