1-(3-ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-3-(2-ethyl-6-methyl-pyridin-4-yl)-propan-1-one | 945463-73-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(3-ethyl-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-3-(2-ethyl-6-methyl-pyridin-4-yl)-propan-1-one
• 英文别名: 1-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-3-(2-ethyl-6-methylpyridin-4-yl)propan-1-one
• CAS: 945463-73-0
• 化学式: C₂₃H₃₁NOS
• 分子量: 369.571
• InChiKey: LCFCVZQHJDMWKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  58.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Novel Pyridine Derivatives
  申请人：Bolli Martin

  公开号：US20090005421A1

  公开（公告）日：2009-01-01

  The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

  这项发明涉及新型吡啶衍生物，它们的制备以及它们作为药用活性化合物的用途。这些化合物特别作为免疫抑制剂。
• NOVEL PYRIDINE DERIVATIVES
  申请人：Bolli Martin

  公开号：US20120195930A1

  公开（公告）日：2012-08-02

  The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

  本发明涉及新型吡啶衍生物、其制备和作为药物活性化合物的用途。这些化合物特别作为免疫抑制剂。
• US8178562B2
  申请人：——

  公开号：US8178562B2

  公开（公告）日：2012-05-15
• US8697732B2
  申请人：——

  公开号：US8697732B2

  公开（公告）日：2014-04-15
• [EN] NOVEL PYRIDINE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS DE PYRIDINE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2007086001A2

  公开（公告）日：2007-08-02

  [EN] The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
  [FR] Cette invention concerne de nouveaux dérivés de pyridine, leur préparation et leur utilisation comme composés pharmaceutiquement actifs. Ces composés servent en particulier d'agents immunosuppresseurs.