2-Methoxypentan-1-ol | 1779926-02-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Methoxypentan-1-ol
• CAS: 1779926-02-1
• 化学式: C₆H₁₄O₂
• 分子量: 118.17
• InChiKey: WGWLUEYOKURLOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Process for producing optically active amide from alpha beta- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20030120067A1

  公开（公告）日：2003-06-26

  A novel process for producing an optically active amide excellent in chemical selectivity and enantioselectivity by asymmetric hydrogenation of an &agr;,&bgr;-unsaturated amide and also allowing the reaction to proceed efficiently even when a trace amount of a catalyst is used relative to the substrate as compared with the amount in a conventional process. An optically active amide is produced by asymmetric hydrogenation of an &agr;,&bgr;-unsaturated amide derivative in the presence of a transition metal complex containing a specific phosphine-phosphorane compound.

  一种生产光学活性酰胺的新工艺，具有优异的化学选择性和对映选择性，通过对α，β-不饱和酰胺进行不对称加氢实现，并且即使相对于底物而言使用微量催化剂，也能使反应高效进行，相较于传统工艺中使用的量。在含有特定膦-膦烷化合物的过渡金属配合物存在下，通过对α，β-不饱和酰胺衍生物进行不对称加氢，生产出光学活性酰胺。
• COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS
  申请人：Gasser Robin Beat

  公开号：US20100137294A1

  公开（公告）日：2010-06-03

  The present application discloses the Tv-stp-1 serine/threonine phosphatase gene from Trichostrongylus vitrinus , and compounds that are useful as invertebrate control agents.

  本申请披露了Trichostrongylus vitrinus的Tv-stp-1丝氨酸/苏氨酸磷酸酶基因以及作为无脊椎动物控制剂有用的化合物。
• Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0567271A2

  公开（公告）日：1993-10-27

  Compounds of formula (I): [wherein : R1 is hydrogen, alkyl, aryl-substituted alkyl or aromatic heterocyclic-substituted alkyl ; R2 is: aryl-substituted alkyl, aromatic heterocyclic-substituted alkyl or diarylamino; and R3 is carboxy or a group of formula -CONHS02 R4 wherein R4 is alkyl] ; and pharmaceutically acceptable salts and esters thereof have valuable 5α-reductase inhibitory activity and can thus be used for the treatment and prophylaxis of, inter alia, prostatic hypertrophy as well as other disorders arising from excess levels of 5α-dihydro-testosterone.

  式(I)化合物： [其中 ：R1 是氢、烷基、芳基取代的烷基或芳香杂环取代的烷基；R2 是：芳基取代的烷基、芳香杂环取代的烷基或二芳基氨基；以及 R3 是羧基或式 -CONHS02 R4 的基团，其中 R4 是烷基]；及其药学上可接受的盐类和酯类具有重要的 5α 还原酶抑制活性，因此可用于治疗和预防前列腺肥大以及因 5α 二氢睾酮水平过高而引起的其他疾病。
• Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0725074A2

  公开（公告）日：1996-08-07

  A compound of formula (IV) and a process for the preparation of a compound of the following formula: in which R10 is a hydroxy group, a group -OR5, in which R5 is a carboxy protecting group, a group -NR1R2, in which R1 is hydrogen, alkyl, aryl-substituted alkyl or aromatic heterocyclic-substituted alkyl and R2 is aryl-substituted alkyl, aromatic heterocyclic-substituted alkyl or diarylamino, or a group -NRR', in which R and R' are hydrogen or alkyl.

  式(IV)化合物 以及制备下式化合物的工艺： 其中 R10 是羟基、基团-OR5（其中 R5 是羧基保护基）、基团-NR1R2（其中 R1 是氢、烷基、芳基取代的烷基或芳香杂环取代的烷基，R2 是芳基取代的烷基、芳香杂环取代的烷基或二芳基氨基）或基团-NRR'（其中 R 和 R' 是氢或烷基）。
• Process for producing an optically active amide from an alpha, beta-unsaturated amide derivative in the presence of a transition metal complex containing a phosphine-phosphorane compound and a transition metal
  申请人：Takasago International Corporation

  公开号：EP1279660A1

  公开（公告）日：2003-01-29

  A novel process for producing an optically active amide excellent in chemical selectivity and enantioselectivity by asymmetric hydrogenation of an α,β-unsaturated amide and also allowing the reaction to proceed efficiently even when a trace amount of a catalyst is used relative to the substrate as compared with the amount in a conventional process. An optically active amide is produced by asymmetric hydrogenation of an α,β-unsaturated amide derivative in the presence of a transition metal complex containing a specific phosphine-phosphorane compound.

  一种通过 α，β-不饱和酰胺的不对称氢化反应生产光学活性酰胺的新工艺，该工艺具有极佳的化学选择性和对映体选择性，与传统工艺相比，即使相对于底物使用微量催化剂，反应也能高效进行。在含有特定膦-膦化合物的过渡金属复合物存在下，α,β-不饱和酰胺衍生物通过不对称氢化反应生成光学活性酰胺。